Myles Garrett had the most sacks per game played when playing 25+ games, with 1.2.

most defensive sacks per game by a player minimum 25 games played

	NAME	SCK/GP	GP	SCK	TKL	AST	COMB	SCKY	INT	INT YDS	INT TD	FF	FR	FR TD
1	Myles Garrett M. Garrett	1.2	27	32.5	71	12	83	190	1	4	0	7	1	0
2	Jaylon Ferguson J. Ferguson	1.05	43	45.0	111	30	141	290.5	0	0	0	8	4	0
3	Sutton Smith S. Smith	1.03	29	30.0	89	19	108	201.5	0	0	0	7	6	3
4	Chase Young C. Young	0.98	31	30.5	74	14	88	222	0	0	0	9	0	0
5	Hunter Dimick H. Dimick	0.98	29	28.5	65	15	80	147.5	0	0	0	4	2	0
6	Derek Barnett D. Barnett	0.97	34	33.0	108	20	128	197	1	7	0	3	2	0
7	Anthony Winbush A. Winbush	0.96	26	25.0	49	10	59	139				9	2	0
8	Ejuan Price E. Price	0.94	27	25.5	65	16	81	186.5				4	1	1
9	Ja'Von Rolland-Jones J. Rolland-Jones	0.91	47	43.0	94	36	130	244.5	1	2	0	10	2	0
10	Josh Allen J. Allen	0.9	35	31.5	130	21	151	202	1	14	0	11	2	0
11	Ken Ekanem K. Ekanem	0.9	25	22.5	40	13	53	136	0	0	0	2	0	0
12	Emmanuel Ogbah E. Ogbah	0.88	32	28.0	67	14	81	166	0	0	0	5	2	1
13	Curtis Weaver C. Weaver	0.87	39	34.0	73	30	103	214.5	2	17	0	3	1	1
14	Ifeadi Odenigbo I. Odenigbo	0.87	27	23.5	40	5	45	162.5	0	0	0	5	2	0
15	Trey Hendrickson T. Hendrickson	0.85	34	29.0	67	24	91	184	0	0	0	7	2	0
16	Jordan Willis J. Willis	0.84	29	24.5	70	15	85	155.5	0	0	0	4	2	0
17	Will Anderson Jr. W. Anderson Jr.	0.84	41	34.5	128	66	194	200.5	1	25	1	1	0	0
18	Yannick Ngakoue Y. Ngakoue	0.83	26	21.5	44	13	57	131.5	1	3	0	2	0	0
19	Demarcus Walker D. Walker	0.81	35	28.5	100	19	119	187.5	1	0	0	8	2	0
20	Oshane Ximines O. Ximines	0.81	40	32.5	94	35	129	199.5	1	14	0	11	3	0
21	Harold Landry H. Landry	0.81	32	26.0	91	30	121	211	1	20	0	9	1	0
22	Porter Gustin P. Gustin	0.81	26	21.0	72	14	86	136.5	0	0	0	0	1	0
23	Arden Key A. Key	0.81	26	21.0	76	32	108	135				4	2	0
24	Joe Jackson J. Jackson	0.81	31	25.0	76	21	97	129	1	42	1	5	2	0
25	Marquis Haynes M. Haynes	0.8	40	32.0	96	26	122	262	1	17	0	12	3	0