Between the 2004 and 2016 seasons, Case Keenum had the most passing yards, with 19,217 yards.

	NAME	YDS	GP	CMP	ATT	PCT	AVG	YDS/G	TD	INT	RTG	TD%	INT%	SCK	SCKY
1	Case Keenum C. Keenum	19,217	57	1,546	2,229	69.4	8.6	337.1	155	46	160.6	7.0	2.1
2	Landry Jones L. Jones	16,646	52	1,388	2,183	63.6	7.6	320.1	123	52	141.5	5.6	2.4
3	Graham Harrell G. Harrell	15,793	45	1,403	2,010	69.8	7.9	351.0	134	34	154.4	6.7	1.7
4	Kellen Moore K. Moore	14,667	53	1,157	1,658	69.8	8.8	276.7	142	28	169.0	8.6	1.7
5	Colt Brennan C. Brennan	14,193	38	1,115	1,584	70.4	9.0	373.5	131	42	167.6	8.3	2.7
6	Rakeem Cato R. Cato	14,079	53	1,153	1,838	62.7	7.7	265.6	131	44	145.8	7.1	2.4
7	Sean Mannion S. Mannion	13,600	47	1,187	1,838	64.6	7.4	289.4	83	54	135.8	4.5	2.9
8	Corey Robinson C. Robinson	13,472	48	1,179	1,823	64.7	7.4	280.7	81	48	136.1	4.4	2.6
9	Colt McCoy C. McCoy	13,253	53	1,157	1,645	70.3	8.1	250.1	112	45	155.0	6.8	2.7
10	Aaron Murray A. Murray	13,166	52	921	1,478	62.3	8.9	253.2	121	41	158.6	8.2	2.8
11	Dan Lefevour D. Lefevour	12,905	53	1,171	1,763	66.4	7.3	243.5	102	36	142.9	5.8	2.0
12	Cooper Rush C. Rush	12,894	50	1,022	1,648	62.0	7.8	257.9	90	55	139.1	5.5	3.3	95	674
13	Brandon Doughty B. Doughty	12,856	43	1,023	1,491	68.6	8.6	299.0	111	34	161.0	7.4	2.3
14	Derek Carr D. Carr	12,848	45	1,087	1,630	66.7	7.9	285.5	113	24	152.8	6.9	1.5
15	Ryan Lindley R. Lindley	12,690	49	961	1,732	55.5	7.3	259.0	90	47	128.8	5.2	2.7
16	Chase Daniel C. Daniel	12,515	51	1,094	1,609	68.0	7.8	245.4	101	41	148.9	6.3	2.5
17	Trevor Vittatoe T. Vittatoe	12,439	49	914	1,641	55.7	7.6	253.9	97	42	133.8	5.9	2.6
18	Matt Barkley M. Barkley	12,327	47	1,001	1,562	64.1	7.9	262.3	116	48	148.7	7.4	3.1
19	Jared Goff J. Goff	12,200	37	977	1,569	62.3	7.8	329.7	96	30	144.0	6.1	1.9	82	592
20	Zach Terrell Z. Terrell	12,104	49	908	1,387	65.5	8.7	247.0	96	31	157.1	6.9	2.2	74	417
21	Zac Dysert Z. Dysert	12,013	46	1,066	1,672	63.8	7.2	261.2	73	51	132.4	4.4	3.1
22	Nick Mullens N. Mullens	11,994	44	928	1,546	60.0	7.8	272.6	87	46	137.8	5.6	3.0	64	476
23	Shane Carden S. Carden	11,991	40	1,052	1,579	66.6	7.6	299.8	86	30	144.6	5.4	1.9
24	Tajh Boyd T. Boyd	11,904	47	901	1,402	64.3	8.5	253.3	107	39	155.2	7.6	2.8
25	Chase Holbrook C. Holbrook	11,846	36	1,086	1,565	69.4	7.6	329.1	85	41	145.7	5.4	2.6