From 2000 through 2019, 5 teams were tied for the highest winning percentage, winning 100.0 percent of the time. The first three are the McNeese Cowboys, the Nicholls Colonels and the Bethune-Cookman Wildcats.

	TEAM	W%	GP	W	L	T	TD	PTS	PPG	OPP PTS	OPP PPG	1DWN	3DWN%	4DWN%
1	McNeese	1.000	1	1	0	0		30	30.0	27	27.0	27
2	Nicholls	1.000	1	1	0	0		42	42.0	25	25.0	20
3	Bethune-Cookman	1.000	1	1	0	0		58	58.0	52	52.0	29
4	Eastern Washington	1.000	1	1	0	0		35	35.0	17	17.0	26
5	Rhode Island	1.000	1	1	0	0		26	26.0	21	21.0	18
6	Ohio State	.842	260	219	41	0	1,148	8,992	34.6	4,493	17.3	5,651
7	Boise State	.832	262	218	44	0	1,282	10,265	39.2	5,359	20.5	5,900
8	Oklahoma	.816	266	217	49	0	1,341	10,375	39.0	5,777	21.7	6,296
9	Appalachian State	.782	78	61	17	0	360	2,748	35.2	1,552	19.9	1,707	42.1	60.9
10	LSU	.772	259	200	59	0	1,035	8,224	31.8	4,713	18.2	5,376
11	Alabama	.762	265	202	63	0	1,091	8,706	32.9	4,191	15.8	5,592
12	Georgia	.749	263	197	66	0	1,013	8,246	31.4	5,097	19.4	5,435
13	Clemson	.739	264	195	69	0	1,113	8,773	33.2	5,195	19.7	5,900
14	USC	.729	258	188	70	0	1,123	8,630	33.4	5,576	21.6	5,791
15	Oregon	.727	256	186	70	0	1,264	9,625	37.6	6,469	25.3	5,986
16	TCU	.725	251	182	69	0	1,032	8,280	33.0	5,053	20.1	5,528
17	Wisconsin	.708	264	187	77	0	1,038	8,164	30.9	5,225	19.8	5,556
18	Florida	.706	255	180	75	0	998	7,880	30.9	4,765	18.7	5,201
19	Texas	.706	255	180	75	0	1,116	8,743	34.3	5,662	22.2	5,628
20	Virginia Tech	.695	262	182	80	0	972	7,837	29.9	5,020	19.2	5,247
21	Florida State	.692	260	180	80	0	1,024	8,318	32.0	5,364	20.6	5,469
22	Auburn	.681	257	175	82	0	944	7,563	29.4	5,319	20.7	5,201
23	Utah	.669	251	168	83	0	928	7,469	29.8	5,225	20.8	5,110
24	Miami	.657	251	165	86	0	945	7,535	30.0	5,143	20.5	4,871
25	Michigan	.657	251	165	86	0	958	7,589	30.2	5,284	21.1	5,172