Donnel Pumphrey and Damion Fletcher were tied for the most games with 50+ rushing yards, with 47 games.

Interpreted as:

Most 50+ rushing yard games by a player

	NAME	GP	RUSH YDS	ATT	YPC	RUSH YDS/G	RUSH TD	REC YDS	REC	TRG	AVG	REC YDS/G	REC TD
1	Donnel Pumphrey D. Pumphrey	47	6,275	1,014	6.2	133.5	62	897	87	118	10.3	19.1	4
2	Damion Fletcher D. Fletcher	47	5,209	975	5.3	110.8	44	749	97		7.7	15.9	2
3	Myles Gaskin M. Gaskin	46	5,139	890	5.8	111.7	56	426	59	83	7.2	9.3	5
4	Royce Freeman R. Freeman	44	5,416	873	6.2	123.1	56	777	74	85	10.5	17.7	4
5	Marquez Cooper M. Cooper	42	4,754	977	4.9	113.2	44	370	44	60	8.4	8.8	2
6	Travis Etienne T. Etienne	42	4,504	562	8.0	107.2	59	819	77	96	10.6	19.5	6
7	Jahwan Edwards J. Edwards	42	4,319	806	5.4	102.8	48	326	48		6.8	7.8	0
8	Avon Cobourne A. Cobourne	42	5,008	1,005	5.0	119.2		426	53		8.0	10.1
9	Kaytron Allen K. Allen	41	3,818	648	5.9	93.1	36	369	54	79	6.8	9.0	2
10	Devin Neal D. Neal	41	4,096	692	5.9	99.9	45	665	70	88	9.5	16.2	3
11	Cedric Benson C. Benson	41	5,309	1,030	5.2	129.5	59	553	61		9.1	13.5	3
12	Justin Jackson J. Jackson	40	5,056	998	5.1	126.4	38	652	92	119	7.1	16.3	1
13	DeAngelo Williams D. Williams	40	5,973	942	6.3	149.3	54	709	67		10.6	17.7	5
14	Ron Dayne R. Dayne	40	6,198	1,071	5.8	155.0		246	23		10.7	6.2
15	Jonathan Taylor J. Taylor	39	6,087	900	6.8	156.1	50	377	39	62	9.7	9.7	5
16	Tyrell Fenroy T. Fenroy	39	4,503	755	6.0	115.5	47	511	49		10.4	13.1	1
17	TreVeyon Henderson T. Henderson	38	3,486	512	6.8	91.7	41	648	71	86	9.1	17.1	3
18	Travis Dye T. Dye	38	3,550	540	6.6	93.4	23	817	80	99	10.2	21.5	6
19	Rodney Smith R. Smith	38	3,699	732	5.1	97.3	24	464	54	64	8.6	12.2	0
20	Nick Chubb N. Chubb	38	4,576	683	6.7	120.4	43	329	28	36	11.8	8.7	3
21	Stepfan Taylor S. Taylor	38	3,979	755	5.3	104.7	37	612	84		7.3	16.1	4
22	Demarco Murray D. Murray	38	3,415	652	5.2	89.9	46	1,112	108		10.3	29.3	12
23	Dontrell Moore D. Moore	38	4,783	941	5.1	125.9	50	715	76		9.4	18.8	7
24	Mewelde Moore M. Moore	38	4,162	821	5.1	109.5	20	1,819	166		11.0	47.9	13
25	Ricky Williams R. Williams	38	5,837	903	6.5	153.6		844	69		12.2	22.2