Alisson has 19 clean sheets, 76 goals allowed and 163 saves in 62 appearances in the Premier League against Big Six opponents in his career.

Alisson stats against the big six in his career

	NAME	DATE	CLUB		OPP	MIN	GC	SV	SV-PK	CS	ERR-SH	ERR-G	PKC	OG	TKL	FOUL	YC	RC
1	Alisson	9/15/2018	Liverpool	@	Tottenham	90	1	2	0	0	0	0	0	0	0	0	0	0
2	Alisson	9/29/2018	Liverpool	@	Chelsea	90	1	3	0	0	0	0	0	0	0	0	0	0
3	Alisson	10/7/2018	Liverpool	vs	Man City	90	0	2	0	1	0	0	0	0	0	0	0	0
4	Alisson	11/3/2018	Liverpool	@	Arsenal	90	1	3	0	0	1	0	0	0	0	0	0	0
5	Alisson	12/16/2018	Liverpool	vs	Man United	90	1	2	0	0	0	1	0	0	0	0	0	0
6	Alisson	12/29/2018	Liverpool	vs	Arsenal	90	1	1	0	0	0	0	0	0	0	0	0	0
7	Alisson	1/3/2019	Liverpool	@	Man City	90	2	2	0	0	0	0	0	0	0	0	0	0
8	Alisson	2/24/2019	Liverpool	@	Man United	90	0	3	0	1	0	0	0	0	1	0	0	0
9	Alisson	3/31/2019	Liverpool	vs	Tottenham	90	1	1	0	0	1	0	0	0	0	0	0	0
10	Alisson	4/14/2019	Liverpool	vs	Chelsea	90	0	3	0	1	0	0	0	0	0	0	0	0
11	Alisson	10/20/2019	Liverpool	@	Man United	90	1	1	0	0	0	0	0	0	0	0	0	0
12	Alisson	10/27/2019	Liverpool	vs	Tottenham	90	1	3	0	0	0	0	0	0	0	0	0	0
13	Alisson	11/10/2019	Liverpool	vs	Man City	90	1	2	0	0	0	0	0	0	0	0	0	0
14	Alisson	1/11/2020	Liverpool	@	Tottenham	90	0	4	0	1	0	0	0	0	0	0	0	0
15	Alisson	1/19/2020	Liverpool	vs	Man United	90	0	4	0	1	0	0	0	0	0	0	0	0
16	Alisson	7/2/2020	Liverpool	@	Man City	90	4	2	0	0	0	0	0	0	0	0	0	0
17	Alisson	7/15/2020	Liverpool	@	Arsenal	90	2	0	0	0	0	1	0	0	0	0	0	0
18	Alisson	7/22/2020	Liverpool	vs	Chelsea	90	3	2	0	0	0	0	0	0	0	0	0	0
19	Alisson	9/20/2020	Liverpool	@	Chelsea	90	0	3	1	1	0	0	0	0	0	0	0	0
20	Alisson	9/28/2020	Liverpool	vs	Arsenal	90	1	2	0	0	0	0	0	0	0	0	0	0
21	Alisson	11/8/2020	Liverpool	@	Man City	90	1	1	0	0	0	0	0	0	0	0	0	0
22	Alisson	12/16/2020	Liverpool	vs	Tottenham	90	1	1	0	0	1	0	0	0	0	0	0	0
23	Alisson	1/17/2021	Liverpool	vs	Man United	90	0	4	0	1	0	0	0	0	0	0	0	0
24	Alisson	1/28/2021	Liverpool	@	Tottenham	90	1	1	0	0	0	0	0	0	0	0	0	0
25	Alisson	2/7/2021	Liverpool	vs	Man City	90	4	1	0	0	0	2	0	0	0	0	0	0
	Total					5,580	76	163	1	19	5	6	0	0	2	0	0	0