Kevin De Bruyne has the most career assists by a Manchester City player in the Premier League, with 109 assists.

NAME	A	M	MIN	START	G	G/M	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
Kevin De Bruyne	109	257	19,605	225	68	0.26	177	4	4	625	223	27	18,290	798	28
David Silva	90	309	23,994	281	59	0.19	149	0
Sergio Agüero	47	275	19,869	235	184	0.67	231	27
Bernardo Silva	41	233	16,117	179	39	0.17	80	0	0	274	109	7	13,492	970	21
Raheem Sterling	41	225	17,134	193	91	0.40	132	3	1	508	213	17	11,312	1,569	83
Riyad Mahrez	34	145	8,648	95	43	0.30	77	6	2	290	115	10	6,806	650	39
Samir Nasri	32	129	8,602	99	18	0.14	50	0
Gabriel Jesus	29	159	9,308	99	58	0.36	87	3	0	343	161	10	5,030	797	82
Yaya Touré	29	230	18,245	211	62	0.27	91	11
Leroy Sané	28	90	6,088	68	25	0.28	53	0	0	148	58	7	4,151	542	37
Phil Foden	27	164	9,725	108	54	0.33	81	0	2	301	133	9	7,257	714	28
James Milner	24	147	8,446	89	13	0.09	37	1
Carlos Tévez	24	113	8,415	97	58	0.51	82	12
Jesús Navas	23	123	7,362	77	4	0.03	27	0
Niall Quinn	23	121	9,175	101	30	0.25	53	0
Rodri	21	172	13,980	161	22	0.13	43	1	0	213	68	4	16,738	279	12
Fernandinho	19	264	20,198	224	20	0.08	39	0
Aleksandar Kolarov	19	165	11,857	129	11	0.07	30	0
Pablo Zabaleta	19	230	18,405	203	9	0.04	28	0
Shaun Wright-Phillips	19	178	13,248	145	27	0.15	46	0
Kyle Walker	18	197	16,384	184	3	0.02	21	0	0	87	17	1	17,091	197	18
Stephen Ireland	18	138	9,658	109	16	0.12	34	0
Ilkay Gündogan	16	188	12,618	138	44	0.23	60	3	2	290	95	8	12,291	433	11
Gareth Barry	15	132	10,837	123	6	0.05	21	0
Joey Barton	15	130	10,994	123	15	0.12	30	2