Dejan Stanković has made the most career appearances by a Serbian in Serie A, with 368 appearances.

	NAME	M	Rating	MIN	START	G	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Dejan Stanković D. Stanković	368		27,061	306	51	0.14	7	58	0
2	Ivan Radovanović I. Radovanović	337		24,261	273	4	0.01	5	9	0
3	Siniša Mihajlović S. Mihajlović	315		26,387	304	38	0.12			8
4	Darko Lazović D. Lazović	295		21,031	240	21	0.07	41	62	2	1	304	94	11	12,415	685	76
5	Sergej Milinković-Savić S. Milinković-Savić	267		21,560	247	57	0.21	44	101	0	6	554	185	11	17,997	758	59
6	Nenad Tomović N. Tomović	250		19,533	220	3	0.01	5	8	0
7	Adem Ljajić A. Ljajić	225		13,827	156	48	0.21	39	87	6
8	Nikola Milenković N. Milenković	216		18,124	202	14	0.06	2	16	0	0	141	53	6	13,310	195	3
9	Dušan Vlahović D. Vlahović	215		14,231	159	90	0.42	17	107	21	5	565	216	13	5,585	931	117
10	Vladimir Jugović V. Jugović	202		15,671	179	31	0.15			2
11	Dušan Basta D. Basta	200		15,921	181	10	0.05	13	23	0
12	Aleksandar Kolarov A. Kolarov	192		15,501	172	23	0.12	14	37	6
13	Filip Đuričić F. Đuričić	163		9,345	114	17	0.10	14	31	1	0	178	60	5	5,641	299	17
14	Boško Janković B. Janković	161		9,561	109	20	0.12	7	27	0
15	Vanja Milinković-Savić V. Milinković-Savić	157		14,024	156	0	0.00	0	0	0	0	1	0	0	7,568	2	0
16	Saša Lukić S. Lukić	151		9,898	109	13	0.09	5	18	4	0	100	29	1	6,463	146	5
17	Nikola Maksimović N. Maksimović	147		11,913	131	2	0.01	6	8	0
18	Ivan Ilić I. Ilić	142		9,778	111	9	0.06	8	17	0	0	86	27	3	7,201	100	4
19	Lazar Samardzic L. Samardzic	135	6.89	6,341	60	16	0.12	10	26	1	0	165	57	7	4,238	166	1
20	Zdravko Kuzmanović Z. Kuzmanović	128		8,087	95	3	0.02	2	5	0
21	Aleksandar Luković A. Luković	107		8,462	94	0	0.00			0
22	Nikola Lazetić N. Lazetić	106		6,084	74	2	0.02			0
23	Željko Brkić Ž. Brkić	86		7,582	85	0	0.00	1	1	0
24	Filip Đorđević F. Đorđević	81		3,852	41	12	0.15	5	17	0	0	74	35	1	1,487	30	45
25	Nenad Krstičić N. Krstičić	79		5,041	56	2	0.03	3	5	0