Alan Shearer has the most career goals in the Premier League against Man City, with 11 goals.

most goals by a player scored against man city all-time

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Alan Shearer A. Shearer	11	17	1,436	16	0.65	2	13	1
2	Mohamed Salah M. Salah	9	16	1,303	15	0.56	6	15	3	0	39	19	2	547	94	10
3	Wayne Rooney W. Rooney	9	27	2,128	24	0.33	3	12	0
4	Jamie Vardy J. Vardy	8	19	1,517	18	0.42	1	9	2	0	31	16	2	383	51	15
5	Jermain Defoe J. Defoe	8	24	1,416	15	0.33	1	9	0
6	Robbie Keane R. Keane	8	17	1,041	11	0.47	2	10	1
7	Ian Rush I. Rush	8	8	720	8	1.00	0	8	0
8	Sadio Mané S. Mané	7	16	1,338	16	0.44	1	8	0	0	25	13	2	730	47	18
9	Darren Bent D. Bent	7	14	1,098	12	0.50	0	7	1
10	Jimmy Floyd Hasselbaink J. Floyd Hasselbaink	7	10	676	8	0.70	2	9	0
11	Frank Lampard F. Lampard	7	21	1,771	20	0.33	4	11	3
12	Michael Owen M. Owen	7	9	524	6	0.78	0	7	0
13	Eric Cantona E. Cantona	7	7	585	6	1.00	3	10	1
14	Marcus Rashford M. Rashford	6	17	1,174	13	0.35	1	7	2	0	21	10	2	389	43	3
15	Dion Dublin D. Dublin	6	8	644	7	0.75	0	6	0
16	Anthony Martial A. Martial	5	14	792	9	0.36	0	5	2	0	19	13	0	386	32	3
17	Son Heung-min S. Heung-min	5	18	1,357	15	0.28	5	10	0	0	31	18	0	616	42	17
18	Philippe Coutinho P. Coutinho	5	9	559	7	0.56	1	6	0
19	Harry Kane H. Kane	5	14	1,214	13	0.36	2	7	1
20	Andy Carroll A. Carroll	5	14	825	9	0.36	0	5	0
21	Theo Walcott T. Walcott	5	21	1,277	15	0.24	0	5	0
22	Didier Drogba D. Drogba	5	15	887	10	0.33	2	7	0
23	Tim Cahill T. Cahill	5	15	1,171	13	0.33	2	7	0
24	Steed Malbranque S. Malbranque	5	16	1,227	15	0.31	2	7	0
25	Freddie Ljungberg F. Ljungberg	5	9	744	8	0.56	2	7	0