Stefan de Vrij has 3 goals, 3 clean sheets and 3 blocked shots in 18 appearances against Milan in Serie A in his career.
| NAME | DATE | CLUB | OPP | MIN | TKL | TKL-W | TKL-LM | SH-BLK | BLK-CRS | INT | CLR | REC | ERR-SH | ERR-G | PKC | OG | FOUL | YC | RC | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | S. de Vrij | 8/31/2014 |  Lazio | @ |  Milan | 90 | 3 | 3 | 0 | 0 | 1 | 4 | 5 | 8 | 0 | 0 | 1 | 0 | 3 | 1 | 0 |
| 2 | | S. de Vrij | 1/24/2015 | Lazio | vs | Milan | 69 | 2 | 2 | 0 | 0 | 0 | 2 | 7 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3 | | S. de Vrij | 9/20/2016 | Lazio | @ | Milan | 90 | 1 | 1 | 0 | 0 | 0 | 8 | 8 | 7 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
| 4 | | S. de Vrij | 2/13/2017 | Lazio | vs | Milan | 90 | 3 | 3 | 0 | 0 | 1 | 4 | 1 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| 5 | | S. de Vrij | 9/10/2017 | Lazio | vs | Milan | 90 | 1 | 1 | 0 | 0 | 0 | 3 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | | S. de Vrij | 1/28/2018 | Lazio | @ | Milan | 74 | 0 | 0 | 0 | 0 | 0 | 2 | 5 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | | S. de Vrij | 10/21/2018 |  Inter | vs | Milan | 90 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | | S. de Vrij | 3/17/2019 | Inter | @ | Milan | 90 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | | S. de Vrij | 9/21/2019 | Inter | @ | Milan | 90 | 2 | 1 | 0 | 0 | 0 | 2 | 7 | 3 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| 10 | | S. de Vrij | 2/9/2020 | Inter | vs | Milan | 90 | 0 | 0 | 0 | 1 | 0 | 2 | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 11 | | S. de Vrij | 10/17/2020 | Inter | vs | Milan | 90 | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| 12 | | S. de Vrij | 2/21/2021 | Inter | @ | Milan | 90 | 0 | 0 | 0 | 1 | 0 | 4 | 9 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 |
| 13 | | S. de Vrij | 11/7/2021 |  Inter | @ | Milan | 90 | 1 | 0 | 0 | 0 | 0 | 1 | 5 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
| 14 | | S. de Vrij | 2/5/2022 | Inter | vs | Milan | 90 | 1 | 1 | 0 | 0 | 0 | 2 | 1 | 8 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| 15 | | S. de Vrij | 9/3/2022 | Inter | @ | Milan | 84 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | | S. de Vrij | 9/16/2023 | Inter | vs | Milan | 16 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| 17 | | S. de Vrij | 4/22/2024 | Inter | @ | Milan | 2 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18 | | S. de Vrij | 2/2/2025 | Inter | @ | Milan | 90 | 2 | 1 | 0 | 1 | 0 | 2 | 5 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Total | 1,415 | 17 | 13 | 0 | 3 | 2 | 41 | 67 | 65 | 0 | 0 | 1 | 1 | 13 | 2 | 0 |
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