The Houston Astros scored their most runs in a game in 1974 against the Cubs on April 29, 1974, with 18 runs.

Interpreted as:

astros most runs in a regular-season game 1974

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Astros	18	4/29/1974	HOU	vs	CHC	W 18-2	43	20	1	1	2	14	6	0	6	4	0	51	29	4	0	2	0	0	.465	.510	.674	1.184
2	Astros	13	8/6/1974	HOU	@	SFG	W 13-4	45	18	2	2	2	10	3	0	3	0	0	48	30	6	0	0	1	1	.400	.438	.667	1.104
3	Astros	11	7/27/1974	HOU	vs	SFG	W 11-3	33	11	1	0	0	10	6	0	6	2	1	41	12	1	1	1	1	0	.333	.425	.364	.789
4	Astros	11	6/9/1974	HOU	vs	NYM	W 11-1	33	13	4	0	1	9	5	1	9	2	0	42	20	5	1	2	1	0	.394	.463	.606	1.069
5	Astros	11	5/1/1974	HOU	vs	CHC	W 11-7	33	11	2	0	0	9	5	0	6	2	0	40	13	2	0	2	1	1	.333	.400	.394	.794
6	Astros	10	6/11/1974	HOU	vs	PHI	W 10-1	35	11	2	0	1	10	4	0	7	1	0	39	16	3	0	0	3	0	.314	.385	.457	.842
7	Astros	10	4/27/1974	HOU	@	PIT	W 10-7	40	14	2	1	0	10	7	0	4	0	0	49	18	3	1	1	1	0	.350	.438	.450	.888
8	Astros	9	9/29/1974	HOU	@	ATL	W 9-6	38	11	1	1	1	8	4	0	4	0	0	44	17	3	0	2	0	0	.289	.341	.447	.788
9	Astros	9	7/12/1974	HOU	vs	CHC	W 9-4	34	13	2	1	1	8	3	1	5	1	0	39	20	4	0	1	1	1	.382	.436	.588	1.024
10	Astros	9	4/24/1974	HOU	@	STL	W 9-4	36	11	1	0	1	8	5	0	4	0	0	42	15	2	1	0	0	0	.306	.390	.417	.807
11	Astros	9	4/11/1974	HOU	@	SDP	W 9-1	39	14	3	0	1	9	4	1	3	0	0	44	20	4	0	0	0	2	.359	.432	.513	.945
12	Astros	9	4/10/1974	HOU	@	SDP	W 9-1	39	14	2	0	1	9	5	1	7	1	0	45	19	3	0	0	1	1	.359	.444	.487	.932
13	Astros	9	4/9/1974	HOU	@	SDP	W 9-5	39	15	3	0	0	8	3	0	6	1	0	45	18	3	2	1	1	0	.385	.419	.462	.880
14	Astros	8	8/16/1974	HOU	@	MON	W 8-3	38	15	0	1	1	7	3	1	6	0	0	43	20	2	1	0	0	2	.395	.452	.526	.979
15	Astros	8	7/30/1974	HOU	@	CIN	W 8-4	40	13	4	0	2	8	4	1	3	1	1	45	23	6	0	0	1	0	.325	.400	.575	.975
16	Astros	8	7/26/1974	HOU	vs	LAD	W 8-7	45	16	3	0	2	8	1	0	6	0	1	47	25	5	1	0	0	0	.356	.370	.556	.925
17	Astros	8	7/18/1974	HOU	@	STL	W 8-2	41	13	1	0	1	8	2	0	4	0	0	44	17	2	1	0	1	1	.317	.349	.415	.763
18	Astros	8	6/23/1974	HOU	vs	SDP	W 8-2	36	12	3	1	2	7	3	3	12	2	0	42	23	6	0	0	0	1	.333	.429	.639	1.067
19	Astros	8	6/15/1974	HOU	@	CHC	W 8-7	40	15	5	0	1	8	2	0	6	0	1	43	23	6	1	0	0	0	.375	.405	.575	.980
20	Astros	8	5/28/1974	HOU	@	MON	W 8-4	35	11	1	1	1	8	4	0	7	0	0	41	17	3	1	1	0	0	.314	.375	.486	.861
21	Astros	8	5/8/1974	HOU	vs	PIT	W 8-6	41	9	1	0	3	8	10	0	4	1	2	52	19	4	1	0	0	0	.220	.373	.463	.836
22	Astros	8	4/19/1974	HOU	vs	ATL	W 8-2	32	12	0	1	1	7	3	0	6	3	2	38	17	2	1	2	0	1	.375	.405	.531	.937
23	Astros	7	9/17/1974	HOU	@	LAD	W 7-0	36	10	1	0	2	7	3	0	9	0	0	40	17	3	0	1	0	0	.278	.325	.472	.797
24	Astros	7	8/5/1974	HOU	@	SFG	W 7-2	43	19	1	0	0	7	1	0	4	3	0	45	20	1	1	0	0	2	.442	.455	.465	.920
25	Astros	7	7/14/1974	HOU	vs	CHC	W 7-6	47	12	2	0	1	6	4	0	4	0	0	52	17	3	1	0	0	0	.255	.314	.362	.675