George Leclair has the lowest Game Score, with a Game Score of -56 against the Indianapolis Hoosiers on August 16, 1914.

Interpreted as:

lowest game score by a player in history

	NAME	GSC	DATE	TM		OPP	DEC	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP
1	George Leclair G. Leclair	-56	8/16/1914	PTF	@	IND	L	1	22.50	0	1	0	0	8.0	24	20	21	0	8	0	0		51	0
2	Jack Bracken J. Bracken	-47	9/15/1901	CLE	@	DET	L	1	20.57	1	1	0	0	7.0	24	16	21	1	3	2	0		49	1
3	Doc Parker D. Parker	-42	6/21/1901	CIN	@	BKN	L	1	15.75	0	1	0	0	8.0	26	14	21	1	2	0	0		51	1
4	Hod Lisenbee H. Lisenbee	-35	9/11/1936	PHA	@	CWS	L	1	15.75	1	1	0	0	8.0	26	14	17	2	4	0	0		51	1
5	Howard Ehmke H. Ehmke	-34	9/28/1923	BSA	vs	NYY	L	1	24.00	6	0	0	0	6.0	21	16	17	2	4	0	0		42	0
6	Roy Patterson R. Patterson	-33	5/5/1901	CWS	@	MIL	L	1	14.00	2	1	0	0	9.0	25	14	21	1	2	0	0		57	0
7	Tom Sheehan T. Sheehan	-29	9/29/1915	PHA	@	WSH	L	1	13.50	3	1	0	0	8.0	23	12	20	0	4	1	0		52	0
8	Jack Katoll J. Katoll	-29	9/2/1902	BAL	@	CLE	L	1	9.00	0	1	0	0	8.0	23	8	23	1	3	0	0		56	0
9	Roscoe Miller R. Miller	-27	6/24/1901	DET	@	BAL	L	1	15.75	0	1	0	0	8.0	22	14	17	0	3	2	0		50	0
10	Johnny Miljus J. Miljus	-26	7/25/1929	CLE	@	PHA	L	1	42.00	0	0	0	0	3.0	13	14	14	3	3	0	0		25	0
11	Win Noyes W. Noyes	-26	9/5/1919	PHA	vs	BSA	L	1	19.29	3	0	0	0	7.0	22	15	15	1	2	1	0		43	0
12	Casey Patten C. Patten	-25	7/24/1901	WSH	@	CWS	L	1	16.88	1	1	0	0	8.0	20	15	17	0	4	0	0		52	0
13	Flint Rhem F. Rhem	-24	8/4/1933	PHN	vs	NYG	L	1	16.88	1	0	0	0	8.0	21	15	16	0	3	1	0		47	0
14	Clark Griffith C. Griffith	-24	8/25/1902	CWS	@	BAL	L	1	29.25	1	0	0	0	4.0	16	13	14	1	1	1	0			0
15	Carl Doyle C. Doyle	-23	7/28/1936	PHA	@	CWS	L	1	19.29	1	0	0	0	4.2	16	10	15	0	6	2	0		39	1
16	Hugh McQuillan H. McQuillan	-23	9/11/1927	BSN	@	CIN	L	1	20.25	2	0	0	0	6.2	17	15	16	1	3	0	0		39	0
17	Archie Stimmel A. Stimmel	-23	9/23/1901	CIN	vs	BKN	L	1	12.60	1	0	0	0	5.0	20	7	18	2	1	0	0			0
18	Mike Oquist M. Oquist	-21	8/3/1998	OAK	vs	NYY	L	1	25.20	3	0	0	0	5.0	16	14	14	4	3	0	0	0	32	0
19	Johnny Babich J. Babich	-21	6/23/1935	BKN	vs	SLN	L	1	25.07	1	0	0	0	4.2	16	13	13	1	2	0	0		31	0
20	Elmer Myers E. Myers	-21	8/21/1917	PHA	@	CLE	L	1	14.63	1	1	0	0	8.0	21	13	16	0	4	0	0		48	1
21	Al Orth A. Orth	-21	5/7/1903	WSH	@	PHA	L	1	11.25	3	1	0	0	8.0	22	10	19	2	4	0	0		53	1
22	Chubby Dean C. Dean	-20	9/28/1940	PHA	@	BSA	L	1	15.75	1	1	0	0	8.0	19	14	16	1	5	0	0		47	2
23	Heinie Meine H. Meine	-20	6/23/1930	PIT	vs	BKN	L	1	19.50	3	0	0	0	6.0	19	13	14	2	3	0	0		37	0
24	Patsy Flaherty P. Flaherty	-20	5/30/1903	CWS	@	CLE	L	1	14.63	0	1	0	0	8.0	22	13	15	0	2	0	0		48	0
25	Jack Katoll J. Katoll	-20	9/12/1902	BAL	vs	WSH	L	1	15.00	0	1	0	0	9.0	23	15	15	0	1	0	0		49	0