Caledonia Mining (CMCL) had the highest return between 1980 and 1985 by a US stock, returning 379,519.2%.

ASSET	YEARS	% RETURN
Caledonia Mining (CMCL)	1980-1985	379,519.23%
MDU Resources (MDU)	1980-1985	8,437.5%
Service Corporation International (SCI)	1980-1985	1,685.33%
Walmart (WMT)	1980-1985	1,503.66%
Gap (GAP)	1980-1985	1,471.04%
US Bancorp (USB)	1980-1985	950%
Altria (MO)	1980-1985	900%
La-Z-Boy (LZB)	1980-1985	875.33%
PulteGroup (PHM)	1980-1985	831.24%
Home Depot (HD)	1980-1985	814.04%
GlaxoSmithKline PLC ADR (GSK)	1980-1985	785.09%
Berkshire Hathaway (BRK.A)	1980-1985	751.72%
Franklin Resources (BEN)	1980-1985	715.52%
Tootsie Roll Industries (TR)	1980-1985	706.11%
Coca-Cola Consolidated (COKE)	1980-1985	696.2%
SunLink Health Systems (SSY)	1980-1985	683.49%
Seneca Foods Corp B (SENEB)	1980-1985	611.91%
McDonald’s (MCD)	1980-1985	585.68%
PNC Financial Services (PNC)	1980-1985	582.89%
Associated Banc (ASB)	1980-1985	566.2%
Espey Mfg & Electronics (ESP)	1980-1985	555.33%
New York Times (NYT)	1980-1985	547.17%
Newtek Business Services (NEWT)	1980-1985	519.99%
Sysco (SYY)	1980-1985	509.93%
H2O America (HTO)	1980-1985	502.5%