Sapiens International (SPNS) has had the highest return this year by a US stock, returning 53,426.8%.

ASSET	YEAR	% RETURN
Sapiens International (SPNS)	2025	53,426.82%
ZTST (ZTST)	2025	30,631.89%
Seven Hills Realty Trust Right (SEVNR)	2025	27,900%
Regencell Bioscience (RGC)	2025	14,727.84%
QMMM Holdings Limited Ordinary Shares (QMMM)	2025	9,155.81%
Terrestrial Energy (IMSRW)	2025	2,606.9%
Blue Gold Limited Warrant (BGLWW)	2025	2,298.5%
VisionWave Holdings, Inc Warrant (VWAVW)	2025	2,133.33%
New Era Energy & Digital (NUAIW)	2025	1,502.74%
Abivax SA American Depositary Shares (ABVX)	2025	1,487.57%
NovaBay Pharmaceuticals (NBY)	2025	1,258.97%
Diginex Limited Ordinary Shares (DGNX)	2025	1,210.8%
FiEE (FIEE)	2025	1,156.88%
Oncology Institute (TOI)	2025	1,043.79%
Zepp Health (ZEPP)	2025	967.69%
AlphaVest Acquisition Corp Right (ATMVR)	2025	917.27%
XMax (XWIN)	2025	818.18%
Palvella Therapeutics (PVLA)	2025	759%
Relmada Therapeutics (RLMD)	2025	738.47%
Abits (ABTS)	2025	732.29%
Cidara Therapeutics (CDTX)	2025	714.46%
DeFi Development (DFDV)	2025	665.34%
Celcuity LLC (CELC)	2025	665.2%
Hycroft Mining (HYMC)	2025	626.55%
Nanobiotix (NBTX)	2025	611.58%