XPO Logistics (XPO) had the highest return on December 31, 2010 by a large-cap US stock, returning 7.6%.

ASSET	DATE	% RETURN
XPO Logistics (XPO)	12/31/2010	7.56%
Las Vegas Sands (LVS)	12/31/2010	3.72%
First Majestic Silver (AG)	12/31/2010	3.12%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	12/31/2010	2.85%
NVIDIA (NVDA)	12/31/2010	2.68%
United Microelectronics (UMC)	12/31/2010	2.26%
Wynn Resorts (WYNN)	12/31/2010	2.22%
Charter Communications (CHTR)	12/31/2010	2.15%
Nova (NVMI)	12/31/2010	2.09%
Fabrinet (FN)	12/31/2010	2.04%
RBC Bearings (RBC)	12/31/2010	2.01%
Motorola Solutions (MSI)	12/31/2010	1.8%
Invesco (IVZ)	12/31/2010	1.78%
LyondellBasell Industries (LYB)	12/31/2010	1.62%
Wheaton Precious Metals (WPM)	12/31/2010	1.61%
NXP Semiconductors (NXPI)	12/31/2010	1.6%
CGI (GIB)	12/31/2010	1.59%
Lockheed Martin (LMT)	12/31/2010	1.57%
Lennar (LEN.B)	12/31/2010	1.57%
Banco Bilbao Viscaya Argentaria SA ADR (BBVA)	12/31/2010	1.5%
Markel (MKL)	12/31/2010	1.45%
Regions Financial (RF)	12/31/2010	1.45%
ASE Industrial Holding Co Ltd ADR (ASX)	12/31/2010	1.41%
Sterling Construction (STRL)	12/31/2010	1.4%
Natwest (NWG)	12/31/2010	1.4%

Large-cap stocks are treated as having a market cap of $10B+.