Carvana (CVNA) has had the highest return between 2023 and 2025 by a large-cap US stock, returning 7,283.6%.

ASSET	YEARS	% RETURN
Carvana (CVNA)	2023-2025	7,283.58%
Applovin (APP)	2023-2025	5,849.12%
Rigetti Computing (RGTI)	2023-2025	5,265.33%
IREN (IREN)	2023-2025	4,861.07%
Palantir Technologies Inc Class A Common Stock (PLTR)	2023-2025	2,775.08%
Celestica (CLS)	2023-2025	2,566.25%
D-Wave Quantum (QBTS)	2023-2025	2,236%
MicroStrategy (MSTR)	2023-2025	1,929.45%
Robinhood Markets (HOOD)	2023-2025	1,665.86%
IONQ (IONQ)	2023-2025	1,659.1%
Rocket Lab USA (RKLB)	2023-2025	1,604.42%
Ast Spacemobile (ASTS)	2023-2025	1,531.42%
Galaxy Digital (GLXY)	2023-2025	1,374.55%
Vertiv (VRT)	2023-2025	1,295.68%
Oklo (OKLO)	2023-2025	1,286.78%
NVIDIA (NVDA)	2023-2025	1,190.54%
Fortress Transp & Infra Inv (FTAI)	2023-2025	1,056.21%
Credo Technology (CRDO)	2023-2025	1,038.57%
Sterling Construction (STRL)	2023-2025	1,036.47%
Coinbase Global (COIN)	2023-2025	890.49%
Vistra Energy (VST)	2023-2025	794.41%
Kratos Defense & Security Solutions (KTOS)	2023-2025	781.24%
Carpenter Technology (CRS)	2023-2025	781.22%
Comfort Systems USA (FIX)	2023-2025	753.78%
BridgeBio Pharma (BBIO)	2023-2025	716.97%

Large-cap stocks are treated as having a market cap of $10B+.