Verona Pharma PLC ADR (VRNA) had the highest return on December 26, 2019 by a mid-cap US stock, returning 47.1%.

ASSET	DATE	% RETURN
Verona Pharma PLC ADR (VRNA)	12/26/2019	47.07%
Liquidia Technologies (LQDA)	12/26/2019	25%
American Bitcoin (ABTC)	12/26/2019	9.88%
Kinetik (KNTK)	12/26/2019	7.81%
Mirum Pharmaceuticals (MIRM)	12/26/2019	7.47%
Universal Display (OLED)	12/26/2019	6.37%
NexGen Energy (NXE)	12/26/2019	4.92%
Centerra Gold (CGAU)	12/26/2019	4.65%
Applied Opt (AAOI)	12/26/2019	4.5%
Akero Therapeutics (AKRO)	12/26/2019	4.49%
Forward Industries (FORD)	12/26/2019	4.25%
Immunovant (IMVT)	12/26/2019	4.13%
B2Gold (BTG)	12/26/2019	4.12%
Amkor Technology (AMKR)	12/26/2019	3.97%
Sharplink Gaming (SBET)	12/26/2019	3.96%
Cidara Therapeutics (CDTX)	12/26/2019	3.92%
Northern Oil & Gas (NOG)	12/26/2019	3.91%
Arrowhead Pharmaceuticals (ARWR)	12/26/2019	3.78%
Globalstar, Inc Common Stock (GSAT)	12/26/2019	3.65%
Antero Midstream Partners (AM)	12/26/2019	3.61%
Urban Outfitters (URBN)	12/26/2019	3.38%
Osisko Gold Ro (OR)	12/26/2019	3.32%
HUTCHMED DRC (HCM)	12/26/2019	3.25%
Merit Medical Systems (MMSI)	12/26/2019	3.25%
Axsome Therapeutics (AXSM)	12/26/2019	3.15%

Mid-cap stocks are treated as having a market cap between $2B and $10B.