Protalix Biotherapeutics (PLX) had the highest return in December 2003 by a US stock in the Biotechnology Industry, returning 122.2%.

ASSET	MONTH	% RETURN
Protalix Biotherapeutics (PLX)	December 2003	122.22%
Travere Therapeutics (TVTX)	December 2003	108.33%
Arrowhead Pharmaceuticals (ARWR)	December 2003	100%
Opko Health (OPK)	December 2003	47.38%
Anixa Biosciences (ANIX)	December 2003	31.43%
ImmuCell (ICCC)	December 2003	27.27%
Lisata Therapeutics (LSTA)	December 2003	25%
United Therapeutics (UTHR)	December 2003	22.4%
Sangamo Therapeutics (SGMO)	December 2003	19.69%
Inovio Pharmaceuticals (INO)	December 2003	17.92%
Vertex Pharmaceuticals (VRTX)	December 2003	17.75%
Vera Therapeutics (VERA)	December 2003	16.13%
Rigel Pharmaceuticals (RIGL)	December 2003	16.08%
Star Equity (STRR)	December 2003	15.83%
Regeneron Pharmaceuticals (REGN)	December 2003	14.39%
Heron Therapeuti (HRTX)	December 2003	13.95%
Abeona Therapeutics (ABEO)	December 2003	12.69%
Anika Therapeutics (ANIK)	December 2003	10.81%
Lexicon Pharmaceuticals (LXRX)	December 2003	10.3%
Incyte (INCY)	December 2003	10.14%
Ligand Pharmaceuticals (LGND)	December 2003	9.38%
Myriad Genetics (MYGN)	December 2003	8.98%
Ionis Pharmaceuticals (IONS)	December 2003	8.51%
Biocardia (BCDA)	December 2003	7.89%
Amgen (AMGN)	December 2003	6.92%