Super Micro Computer (SMCI) had the highest return between 2022 and 2024 by a large-cap US stock in the S&P 500 (GSPC), returning 583.3%.

ASSET	YEARS	% RETURN
Super Micro Computer (SMCI)	2022-2024	583.25%
Vistra (VST)	2022-2024	547.11%
Constellation Energy (CEG)	2022-2024	505.45%
Fair Isaac (FICO)	2022-2024	355.43%
Vertiv (VRT)	2022-2024	352.51%
NVIDIA (NVDA)	2022-2024	351.16%
Comfort Systems USA (FIX)	2022-2024	332.5%
Palantir Technologies (PLTR)	2022-2024	311.93%
Axon Enterprise (AXON)	2022-2024	279.51%
Broadcom (AVGO)	2022-2024	272.22%
Targa Resources (TRGP)	2022-2024	265.76%
EMCOR (EME)	2022-2024	259.51%
Howmet Aerospace (HWM)	2022-2024	245.09%
Applovin (APP)	2022-2024	240.87%
Deckers Outdoor (DECK)	2022-2024	231.81%
Arista Networks (ANET)	2022-2024	206.84%
TKO (TKO)	2022-2024	200.18%
Royal Caribbean Cruises (RCL)	2022-2024	198.78%
Eli Lilly and (LLY)	2022-2024	189.83%
Texas Pacific Land (TPL)	2022-2024	185.41%
GE Aerospace (GE)	2022-2024	185.08%
Quanta Services (PWR)	2022-2024	176.8%
GE Vernova LLC (GEV)	2022-2024	150.8%
Cardinal Health (CAH)	2022-2024	145.85%
Apollo Global Management LLC Class A (APO)	2022-2024	141.29%

Large-cap stocks are treated as having a market cap of $10B+.