AXIA Energia (AXIA) had the highest return in Q4 2018 by a large-cap US stock, returning 61.6%.

ASSET	QUARTER	% RETURN
AXIA Energia (AXIA)	Q4 2018	61.58%
AngloGold Ashanti (AU)	Q4 2018	45.09%
Gold Fields Ltd ADR (GFI)	Q4 2018	44.85%
Banco Bradesco SA ADR (BBD)	Q4 2018	43.22%
Banco Bradesco S/A ADR (BBDO)	Q4 2018	39.07%
Companhia de Saneamento Basico do Estado de Sao Paulo SABESP ADR (SBS)	Q4 2018	36.32%
Guardant Health (GH)	Q4 2018	35.46%
Banco Santander Brasil SA ADR (BSBR)	Q4 2018	27.37%
Globalstar, Inc Common Stock (GSAT)	Q4 2018	25.49%
Itau Unibanco Banco (ITUB)	Q4 2018	25.23%
Telefonica Brasil SA ADR (VIV)	Q4 2018	24.26%
argenx NV ADR (ARGX)	Q4 2018	23.48%
Kinross Gold (KGC)	Q4 2018	20%
Agnico Eagle Mines (AEM)	Q4 2018	18.77%
ICICI Bank (IBN)	Q4 2018	18.69%
Newmont Goldcorp (NEM)	Q4 2018	15.23%
Starbucks (SBUX)	Q4 2018	13.77%
Embraer (EMBJ)	Q4 2018	13.02%
Franco-Nevada (FNV)	Q4 2018	12.78%
Korea Electric Power Corp ADR (KEP)	Q4 2018	12.51%
Wheaton Precious Metals (WPM)	Q4 2018	12.5%
Procter & Gamble (PG)	Q4 2018	11.31%
Royal Gold (RGLD)	Q4 2018	11.27%
CME (CME)	Q4 2018	11.26%
Church & Dwight (CHD)	Q4 2018	11.04%

Large-cap stocks are treated as having a market cap of $10B+.