best performing large cap stocks 2010 to 2025

QXO (QXO) had the highest return between 2010 and 2025 by a large-cap US stock, returning 4,822,400%.

ASSETYEARS% RETURN
QXO (QXO)
2010-2025
4,822,400%
NVIDIA (NVDA)
2010-2025
43,855.73%
Tesla (TSLA)
2010-2025
35,403.28%
Broadcom (AVGO)
2010-2025
26,373.06%
Axon Enterprise (AXON)
2010-2025
12,633.86%
Netflix (NFLX)
2010-2025
11,721.96%
Texas Pacific Land (TPL)
2010-2025
9,800.79%
Comfort Systems USA (FIX)
2010-2025
8,653.07%
United Rentals (URI)
2010-2025
8,323.74%
Cheniere Energy (LNG)
2010-2025
8,014.97%
Fair Isaac (FICO)
2010-2025
7,910.9%
XPO Logistics (XPO)
2010-2025
7,457.27%
Transdigm (TDG)
2010-2025
6,363.24%
Domino's Pizza Inc Common Stock (DPZ)
2010-2025
6,022.86%
KLA (KLAC)
2010-2025
5,769.52%
Cadence Design Systems (CDNS)
2010-2025
5,101%
Neurocrine Biosciences (NBIX)
2010-2025
5,020.22%
Lam Research (LRCX)
2010-2025
4,972.77%
Nova (NVMI)
2010-2025
4,875.61%
Ensign (ENSG)
2010-2025
4,762.45%
argenx NV ADR (ARGX)
2010-2025
4,598.04%
Eli Lilly and (LLY)
2010-2025
4,481.83%
Fortinet (FTNT)
2010-2025
4,341.28%
Monolithic Power Systems (MPWR)
2010-2025
4,247.73%
Apple (AAPL)
2010-2025
4,147.1%
Large-cap stocks are treated as having a market cap of $10B+.