Carvana (CVNA) has had the highest return between 2023 and 2025 by a large-cap US stock, returning 6,617.7%.

ASSET	YEARS	% RETURN
Carvana (CVNA)	2023-2025	6,617.67%
Applovin (APP)	2023-2025	4,888.62%
IREN (IREN)	2023-2025	3,519.08%
Celestica (CLS)	2023-2025	2,632.95%
Palantir Technologies (PLTR)	2023-2025	2,502.58%
Robinhood Markets (HOOD)	2023-2025	1,304%
MicroStrategy (MSTR)	2023-2025	1,243.45%
IONQ (IONQ)	2023-2025	1,238.66%
NVIDIA (NVDA)	2023-2025	1,157.67%
Vertiv (VRT)	2023-2025	1,105.76%
Ast Spacemobile (ASTS)	2023-2025	1,062.22%
Rocket Lab USA (RKLB)	2023-2025	1,024.94%
Credo Technology (CRDO)	2023-2025	969.65%
Sterling Construction (STRL)	2023-2025	903.98%
Insmed (INSM)	2023-2025	881.11%
Oklo (OKLO)	2023-2025	862.26%
Fortress Transp & Infra Inv (FTAI)	2023-2025	856.54%
Carpenter Technology (CRS)	2023-2025	818.9%
Galaxy Digital (GLXY)	2023-2025	810.55%
BridgeBio Pharma (BBIO)	2023-2025	759.9%
Comfort Systems USA (FIX)	2023-2025	704.76%
Vistra Energy (VST)	2023-2025	685.36%
Spotify Technology (SPOT)	2023-2025	682.39%
Coinbase Global (COIN)	2023-2025	623.35%
Kratos Defense & Security Solutions (KTOS)	2023-2025	582.6%

Large-cap stocks are treated as having a market cap of $10B+.