best performing large cap stocks october 2022 to now

Applied Opt (AAOI) has had the highest return between October 1, 2022 and April 17, 2026 by a large-cap US stock, returning 5,600%.

ASSETDATE% RETURN
Applied Opt (AAOI)
10/1/2022 - 4/17/2026
5,600%
EXACT Sciences (EXAS)
10/1/2022 - 4/17/2026
5,446.69%
Celestica (CLS)
10/1/2022 - 4/17/2026
4,382.06%
Regencell Bioscience (RGC)
10/1/2022 - 4/17/2026
3,599.62%
Vertiv (VRT)
10/1/2022 - 4/17/2026
2,874.44%
Sandisk (SNDK)
10/1/2022 - 4/17/2026
2,522.56%
Applovin (APP)
10/1/2022 - 4/17/2026
2,275.59%
Summit Therapeutics (SMMT)
10/1/2022 - 4/17/2026
1,935%
Sterling Construction (STRL)
10/1/2022 - 4/17/2026
1,908.65%
Rocket Lab USA (RKLB)
10/1/2022 - 4/17/2026
1,903.14%
FTAI Aviation (FTAI)
10/1/2022 - 4/17/2026
1,714.54%
Modine Manufacturing (MOD)
10/1/2022 - 4/17/2026
1,690.33%
Carvana (CVNA)
10/1/2022 - 4/17/2026
1,674.82%
Palantir Technologies (PLTR)
10/1/2022 - 4/17/2026
1,652.73%
IES (IESC)
10/1/2022 - 4/17/2026
1,611.69%
IAMGold (IAG)
10/1/2022 - 4/17/2026
1,587.5%
Comfort Systems USA (FIX)
10/1/2022 - 4/17/2026
1,553.42%
NVIDIA (NVDA)
10/1/2022 - 4/17/2026
1,508.57%
Western Digital (WDC)
10/1/2022 - 4/17/2026
1,343.62%
Credo Technology (CRDO)
10/1/2022 - 4/17/2026
1,334.39%
Carpenter Technology (CRS)
10/1/2022 - 4/17/2026
1,284.59%
Lumentum (LITE)
10/1/2022 - 4/17/2026
1,181.41%
Ast Spacemobile (ASTS)
10/1/2022 - 4/17/2026
1,147.46%
Ciena (CIEN)
10/1/2022 - 4/17/2026
1,103.33%
IREN (IREN)
10/1/2022 - 4/17/2026
1,060.58%
Large-cap stocks are treated as having a market cap of $10B+.