Palantir Technologies (PLTR) had the highest return in April 2025 by a mega-cap US stock, returning 41.2%.

ASSET	MONTH	% RETURN
Palantir Technologies (PLTR)	April 2025	41.18%
Netflix (NFLX)	April 2025	22.02%
GE Vernova LLC (GEV)	April 2025	20.64%
Crowdstrike (CRWD)	April 2025	19.48%
Amphenol (APH)	April 2025	17.36%
Broadcom (AVGO)	April 2025	15.69%
Walmart (WMT)	April 2025	11.09%
Palo Alto Networks (PANW)	April 2025	10.92%
Eli Lilly and (LLY)	April 2025	9.82%
SAP SE ADR (SAP)	April 2025	8.84%
Toyota Motor Corporation ADR (TM)	April 2025	8.77%
Philip Morris International (PM)	April 2025	8.11%
Arm Holdings plc American Depositary Shares (ARM)	April 2025	7.88%
Royal Bank of Canada (RY)	April 2025	7.75%
Tesla (TSLA)	April 2025	6.96%
Arista Networks (ANET)	April 2025	6.64%
Costco Wholesale (COST)	April 2025	5.53%
Microsoft (MSFT)	April 2025	5.5%
Applied Materials (AMAT)	April 2025	4.59%
KLA (KLAC)	April 2025	4.26%
Alphabet Inc Class C (GOOG)	April 2025	3.6%
Alphabet Inc Class A (GOOGL)	April 2025	3.37%
JPMorgan Chase (JPM)	April 2025	1.45%
Coca-Cola (KO)	April 2025	1.21%
Dell Technologies (DELL)	April 2025	1.17%

Mega-cap stocks are treated as having a market cap of $200B+.