Hirequest (HQI) had the highest return between 2000 and 2005 by a US stock in the Nasdaq Composite (IXIC), returning 43,450,200%.

ASSET	YEARS	% RETURN
Hirequest (HQI)	2000-2005	43,450,200%
Cemtrex (CETX)	2000-2005	4,938,903.31%
Live Ventures (LIVE)	2000-2005	1,663,398.44%
Alto Ingredients (ALTO)	2000-2005	794,931.49%
Inseego (INSG)	2000-2005	201,733.33%
NextTrip (NTRP)	2000-2005	191,900%
DeFi Technologies (DEFT)	2000-2005	107,600%
ImmunoPrecise Antibodies (HYFT)	2000-2005	64,185.71%
Xcel Brands (XELB)	2000-2005	9,400%
AlphaTON Capital (ATON)	2000-2005	8,956.6%
Interlink Electronics (LINK)	2000-2005	5,449.74%
Dmc Global (BOOM)	2000-2005	4,728.89%
CBAK Energy Technology (CBAT)	2000-2005	4,320%
Monster Beverage (MNST)	2000-2005	3,581.39%
Broadwind Energy (BWEN)	2000-2005	3,260.13%
Alaunos Therapeutics (TCRT)	2000-2005	2,945.92%
Oramed Pharmaceuticals (ORMP)	2000-2005	2,470.79%
BJs Restaurants (BJRI)	2000-2005	1,825.14%
Yunhong Green CTI (YHGJ)	2000-2005	1,800.41%
Versus Systems Inc. (VS)	2000-2005	1,800%
Middleby (MIDD)	2000-2005	1,504.53%
Penn National Gaming (PENN)	2000-2005	1,369.51%
Odyssey Marine Exploration (OMEX)	2000-2005	1,316%
Sterling Construction (STRL)	2000-2005	1,246.4%
Tractor Supply (TSCO)	2000-2005	1,217.77%