Seaport Therapeutics, Inc Common Stock (SPTX) had the best week in April 2026 by a small-cap US stock the week of April 27, 2026, returning 179,900%.

ASSET	WEEK	% RETURN
Seaport Therapeutics, Inc Common Stock (SPTX)	4/27/2026 - 5/3/2026	179,900%
Mega Fortune Company Limited Ordinary Shares (MGRT)	4/6/2026 - 4/12/2026	225.84%
Mega Fortune Company Limited Ordinary Shares (MGRT)	4/13/2026 - 4/19/2026	152.52%
Zentalis Pharmaceuticals Llc (ZNTL)	4/6/2026 - 4/12/2026	151.33%
Mega Fortune Company Limited Ordinary Shares (MGRT)	3/30/2026 - 4/5/2026	112.02%
POET Technologies (POET)	4/20/2026 - 4/26/2026	106.28%
Artiva Biotherapeutics, Inc Common Stock (ARTV)	4/13/2026 - 4/19/2026	83.75%
agilon health (AGL)	4/6/2026 - 4/12/2026	77.09%
Avanos Medical (AVNS)	4/13/2026 - 4/19/2026	73.38%
Indaptus Therapeutics (INDP)	4/13/2026 - 4/19/2026	64.29%
agilon health (AGL)	4/13/2026 - 4/19/2026	59.59%
InflaRx (IFRX)	4/13/2026 - 4/19/2026	59%
FuelCell Energy (FCEL)	4/20/2026 - 4/26/2026	56.58%
Bandwidth (BAND)	4/27/2026 - 5/3/2026	53.18%
Gloo Holdings, Inc Class A Common Stock (GLOO)	4/13/2026 - 4/19/2026	51.9%
BTQ Technologies Corp Common Stock (BTQ)	4/13/2026 - 4/19/2026	51.07%
Strive Asset Management (ASST)	4/13/2026 - 4/19/2026	49.81%
Inhibrx Biosciences (INBX)	4/20/2026 - 4/26/2026	48.17%
Critical Metals Corp Ordinary Shares (CRML)	4/13/2026 - 4/19/2026	47.59%
Achieve Life Sciences (ACHV)	4/13/2026 - 4/19/2026	46.55%
Beta Bionics, Inc Common Stock (BBNX)	4/13/2026 - 4/19/2026	46.17%
Xerox (XRX)	4/27/2026 - 5/3/2026	46.11%
Swarmer, Inc Common Stock (SWMR)	3/30/2026 - 4/5/2026	44.36%
Innventure (INV)	4/20/2026 - 4/26/2026	43.42%
Taysha Gene Therapies (TSHA)	4/13/2026 - 4/19/2026	43.21%

Small-cap stocks are treated as having a market cap between $300M and $2B.