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best performing stock 2014 large cap

Seaport Therapeutics, Inc Common Stock (SPTX) has had the highest return since January 1, 2026 by a US stock with a market cap of $2,014+, returning 179,000%.

ASSET% RETURN
Seaport Therapeutics, Inc Common Stock (SPTX)
179,000%
DUKE Robotics Corp Common Stock (DUKR)
2,015.3%
Mega Fortune Company Limited Ordinary Shares (MGRT)
1,301.1%
TJGC (TJGC)
1,122.22%
Adlai Nortye Ltd American Depositary Shares (ANL)
992.25%
Moderna (MRNA)
560.41%
Sandisk (SNDK)
558.67%
BUUU (BUUU)
545.02%
Roma Green Finance Limited Ordinary Shares (ROMA)
446.25%
MaxLinear (MXL)
425.52%
Immunitybio (IBRX)
390.59%
agilon health (AGL)
383.15%
Twist Bioscience (TWST)
379.2%
Iovance Biotherapeutics (IOVA)
378.78%
EuroDry (EDRY)
374.55%
10X Genomics (TXG)
373.82%
Dell Technologies (DELL)
351.56%
Matinas BioPharma (MTNB)
338.42%
Quantum (QMCO)
334.23%
AN2 Therapeutics (ANTX)
317.86%
Erasca (ERAS)
316.71%
AXT (AXTI)
316.63%
Aehr Test Systems (AEHR)
314.89%
SIFCO Industries (SIF)
301.43%
Silicom (SILC)
283.02%

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