Constellation Energy (CEG) had the highest return between 2022 and 2024 by a US stock with a market cap of $75B+, returning 505.4%.

ASSET	YEARS	% RETURN
Constellation Energy (CEG)	2022-2024	505.44%
MicroStrategy (MSTR)	2022-2024	426%
NVIDIA (NVDA)	2022-2024	351.13%
Palantir Technologies Inc Class A Common Stock (PLTR)	2022-2024	311.93%
Broadcom (AVGO)	2022-2024	272.22%
Howmet Aerospace (HWM)	2022-2024	245.09%
Applovin (APP)	2022-2024	240.87%
Arista Networks (ANET)	2022-2024	206.84%
Royal Caribbean Cruises (RCL)	2022-2024	198.78%
Petróleo Brasileiro SA - Petrobras (PBR.A)	2022-2024	194.27%
Eli Lilly and (LLY)	2022-2024	189.83%
Petroleo Brasileiro Petrobras SA ADR (PBR)	2022-2024	187.32%
GE Vernova LLC (GEV)	2022-2024	186.24%
GE Aerospace (GE)	2022-2024	185.08%
Apollo Global Management LLC Class A (APO)	2022-2024	141.29%
Mitsubishi UFJ Financial Group Inc ADR (MUFG)	2022-2024	137.78%
Progressive (PGR)	2022-2024	136.78%
Sumitomo Mitsui Financial (SMFG)	2022-2024	135.44%
McKesson (MCK)	2022-2024	134.05%
Interactive Brokers (IBKR)	2022-2024	124.62%
Arm Holdings plc American Depositary Shares (ARM)	2022-2024	119.89%
Dell Technologies (DELL)	2022-2024	119.84%
Mizuho Financial (MFG)	2022-2024	117.55%
Boston Scientific (BSX)	2022-2024	109.72%
Parker-Hannifin (PH)	2022-2024	108.75%