QXO (QXO) had the highest return between 2010 and 2023 by a US stock, returning 28,508,425%.

ASSET	YEARS	% RETURN
QXO (QXO)	2010-2023	28,508,425%
Azitra (AZTR)	2010-2023	3,285,614.29%
Brera Holdings PLC Class B Ordinary Shares (BREA)	2010-2023	1,311,900%
Sequans Communications (SQNS)	2010-2023	852,309.64%
MDxHealth SA ADR (MDXH)	2010-2023	656,566.67%
KULR Technology (KULR)	2010-2023	379,900%
Integra Resources (ITRG)	2010-2023	211,900%
Immatics (IMTX)	2010-2023	210,500%
Blackboxstocks (BLBX)	2010-2023	165,782.35%
Xpel (XPEL)	2010-2023	141,610.53%
BioNexus Gene Lab Corp Common stock (BGLC)	2010-2023	129,168.29%
Iqstel (IQST)	2010-2023	119,085.86%
Next Technology (NXTT)	2010-2023	71,051.36%
Aurora Cannabis (ACB)	2010-2023	63,366.67%
Lottery (SEGG)	2010-2023	55,432.79%
Heart Test Laboratories Inc Common Stock (HSCS)	2010-2023	50,194.12%
GeoVax Labs (GOVX)	2010-2023	43,220%
AquaBounty Technologies (AQB)	2010-2023	39,483.33%
Eastside Distilling (BLNE)	2010-2023	38,638.74%
FingerMotion (FNGR)	2010-2023	32,060%
Alarum Technologies (ALAR)	2010-2023	22,790.86%
Tesla (TSLA)	2010-2023	19,516.33%
Guardforce AI (GFAI)	2010-2023	15,861.54%
Cementos Pacasmayo SAA ADR (CPAC)	2010-2023	14,385.23%
LM Funding America (LMFA)	2010-2023	12,364.65%