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best performing stocks 2013 with market cap above 1 billion

Seaport Therapeutics, Inc Common Stock (SPTX) has had the highest return since January 1, 2026 by a US stock with a market cap of $1B+, returning 215,100%.

ASSET% RETURN
Seaport Therapeutics, Inc Common Stock (SPTX)
215,100%
Mega Fortune Company Limited Ordinary Shares (MGRT)
1,571.84%
Adlai Nortye Ltd American Depositary Shares (ANL)
993.66%
Sandisk (SNDK)
627.56%
Moderna (MRNA)
566.71%
Twist Bioscience (TWST)
476.21%
MaxLinear (MXL)
426.3%
10X Genomics (TXG)
425.51%
Aehr Test Systems (AEHR)
396.62%
Quantum (QMCO)
371.43%
agilon health (AGL)
360.39%
AXT (AXTI)
358.95%
Dell Technologies (DELL)
342.4%
Immunitybio (IBRX)
317.82%
Rackspace Technology  (RXT)
303.99%
Bandwidth (BAND)
298%
Iovance Biotherapeutics (IOVA)
295.68%
Erasca (ERAS)
284.1%
Anterix (ATEX)
273.66%
Pulse Biosciences (PLSE)
273.32%
Abcellera Biologics  (ABCL)
271.35%
Micron Technology (MU)
266.92%
Hyperliquid Strategies Inc Common Stock (PURR)
264.02%
Korsana Biosciences (KRSA)
254.29%
Veradermics (MANE)
242.85%

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