Applied Digital (APLD) had the highest return in April 2021 by a US stock with a market cap of $2B+, returning 417.2%.

ASSET	MONTH	% RETURN
Applied Digital (APLD)	April 2021	417.24%
Celcuity LLC (CELC)	April 2021	90.76%
BioNTech SE (BNTX)	April 2021	70.37%
Privia Health (PRVA)	April 2021	57.91%
ZIM Integrated Shipping Services (ZIM)	April 2021	52.92%
Burford Capital (BUR)	April 2021	38.99%
Galaxy Digital (GLXY)	April 2021	36.6%
Moderna (MRNA)	April 2021	35.26%
Companhia Siderurgica Nacional ADR (SID)	April 2021	34.43%
Genworth Financial (GNW)	April 2021	30.91%
Chord Energy (CHRD)	April 2021	29.67%
Kontoor Brands (KTB)	April 2021	28.17%
Perpetua Resources (PPTA)	April 2021	27.53%
Star Bulk Carriers (SBLK)	April 2021	26.82%
Equifax (EFX)	April 2021	26.46%
Dyne Therapeutics (DYN)	April 2021	25.99%
Teradata (TDC)	April 2021	25.56%
Crocs (CROX)	April 2021	23.45%
Alignment Healthcare LLC (ALHC)	April 2021	23.44%
Avis Budget (CAR)	April 2021	22.82%
Viper Energy Ut (VNOM)	April 2021	22.77%
Pool (POOL)	April 2021	22.21%
Zai Lab (ZLAB)	April 2021	21.79%
Peabody Energy (BTU)	April 2021	21.31%
Century Communities (CCS)	April 2021	21.23%