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best performing stocks in the nasdaq 100 from november 2025

Seaport Therapeutics, Inc Common Stock (SPTX) has had the highest return since November 30, 2025 by a US stock in the Nasdaq Composite (IXIC), returning 184,100%.

ASSET% RETURN
Seaport Therapeutics, Inc Common Stock (SPTX)
184,100%
SharonAI Holdings, Inc Class A Common Stock (SHAZ)
92,281.82%
DUKE Robotics Corp Common Stock (DUKR)
2,251.9%
GMEX ROBOTICS (GMEX)
1,763.12%
Mega Fortune Company Limited Ordinary Shares (MGRT)
1,602.64%
TJGC (TJGC)
1,016.03%
Adlai Nortye Ltd American Depositary Shares (ANL)
940.69%
VerifyMe (VRME)
825.18%
AXT (AXTI)
717.03%
Sandisk (SNDK)
711.93%
Moderna (MRNA)
658.52%
Sellas Life Sciences (SLS)
643.04%
MaxLinear (MXL)
592.81%
Twist Bioscience (TWST)
503.55%
Iovance Biotherapeutics (IOVA)
487.4%
Climb Bio (CLYM)
485.03%
BUUU (BUUU)
455.24%
AN2 Therapeutics (ANTX)
443.81%
Syntec Optics (OPTX)
437.65%
Cumberland Pharmaceuticals (CPIX)
427.33%
10X Genomics (TXG)
407.88%
Aehr Test Systems (AEHR)
380.33%
Erasca (ERAS)
364.98%
Micron Technology (MU)
363.19%
Quantum (QMCO)
358.78%

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