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best performing stocks in the sp500

Seaport Therapeutics, Inc Common Stock (SPTX) has had the highest return since January 1, 2026 by a US stock, returning 160,700%.

ASSET% RETURN
Seaport Therapeutics, Inc Common Stock (SPTX)
160,700%
DUKE Robotics Corp Common Stock (DUKR)
1,782.15%
SharonAI Holdings, Inc Class A Common Stock (SHAZ)
1,726.84%
Mega Fortune Company Limited Ordinary Shares (MGRT)
1,320.05%
VerifyMe (VRME)
1,301.45%
TJGC (TJGC)
1,112.96%
Diana Shipping Inc WT (DSX.WT)
940.36%
Adlai Nortye Ltd American Depositary Shares (ANL)
727.82%
Moderna (MRNA)
624.94%
BUUU (BUUU)
568.56%
Sandisk (SNDK)
506.64%
Roma Green Finance Limited Ordinary Shares (ROMA)
428.74%
Iovance Biotherapeutics (IOVA)
421.58%
MaxLinear (MXL)
397.14%
agilon health (AGL)
389.88%
Immunitybio (IBRX)
385.15%
Twist Bioscience (TWST)
376.93%
Dell Technologies (DELL)
349.93%
10X Genomics (TXG)
340.16%
EuroDry (EDRY)
315.53%
SIFCO Industries (SIF)
299.64%
Erasca (ERAS)
298.38%
Quantum (QMCO)
294.64%
Energys Group Limited Ordinary Shares (ENGS)
293.75%
Penguin Solutions (PENG)
293.36%

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