Applied Digital (APLD) has had the highest return since 2020 by a US stock, returning 2,622,400%.

ASSET	% RETURN
Applied Digital (APLD)	2,622,400%
SharonAI Holdings, Inc Class A Common Stock (SHAZ)	885,028.21%
Integra Resources (ITRG)	521,566.67%
Everbright Digital Holding Limited Ordinary Shares (EDHL)	258,900%
MDxHealth SA ADR (MDXH)	206,263.64%
Synergy CHC Corp Common Stock (SNYR)	103,233.33%
MKDWELL Tech Inc Ordinary Share (MKDW)	66,150%
COSCIENS Biopharma (CSCI)	45,493.22%
authID (AUID)	16,618.75%
Castellum (CTM)	12,300%
Regencell Bioscience (RGC)	9,434.52%
Mingteng International Corporation Inc Ordinary Shares (MTEN)	6,871.43%
Perpetua Resources (PPTA)	6,746.48%
Chord Energy (CHRD)	6,406.3%
XORTX Therapeutics (XRTX)	6,263.64%
Heart Test Laboratories Inc Common Stock (HSCS)	5,694.12%
Foremost Lithium Resource & Technology Ltd Common stock (FMST)	5,277.64%
Celestica (CLS)	4,525.15%
QMMM Holdings Limited Ordinary Shares (QMMM)	3,880%
Azitra (AZTR)	3,757.14%
Aehr Test Systems (AEHR)	3,619%
IsoEnergy (ISOU)	3,598.18%
Innodata (INOD)	3,524.56%
Comfort Systems USA (FIX)	3,303.7%
Zhongchao (ZCMD)	3,261.92%