ETHZilla (ETHZ) has had the highest return since October 16, 2025 by a US stock, returning 823.1%.

ASSET	% RETURN
ETHZilla (ETHZ)	823.08%
Rani Therapeutics (RANI)	234.69%
Artiva Biotherapeutics, Inc Common Stock (ARTV)	98.35%
Apollomics Inc Class A Ordinary Shares (APLM)	83.25%
NextCure (NXTC)	75.7%
VisionWave Holdings, Inc Warrant (VWAVW)	73.44%
Kezar Life Sciences (KZR)	48.6%
Captivision Inc Warrant (CAPTW)	47.41%
VirnetX Holding Corp Common Stock (VHC)	45.19%
Carbon Revolution Public Limited Company Warrant (CREVW)	44.44%
SCHMID Group NV Warrants (SHMDW)	42.88%
GIBO (GIBOW)	40.06%
Carbon Revolution Public Limited Ordinary Shares (CREV)	39.43%
Triller (ILLRW)	37.64%
Drugs Made In America Acquisition Corp Rights (DMAAR)	35.53%
NeuroSense Therapeutics Ltd Warrant (NRSNW)	34.12%
Magnitude International Ltd Ordinary Shares (MAGH)	32.03%
AlphaTime Acquisition Corp Warrant (ATMCW)	31.34%
Sight Sciences (SGHT)	31.01%
Achieve Life Sciences (ACHV)	30.43%
Anghami Inc Warrants (ANGHW)	29.41%
Klotho Neurosciences (KLTOW)	28.83%
Addex Therapeutics (ADXN)	28.37%
XORTX Therapeutics (XRTX)	27.91%
Mingteng International Corporation Inc Ordinary Shares (MTEN)	27.47%