Seaport Therapeutics, Inc Common Stock (SPTX) has had the highest return since October 30, 2025 by a small-cap US stock, returning 236,700%.
| ASSET | % RETURN |
|---|---|
Seaport Therapeutics, Inc Common Stock (SPTX) | 236,700% |
SharonAI Holdings, Inc Class A Common Stock (SHAZ) | 104,995.79% |
Mega Fortune Company Limited Ordinary Shares (MGRT) | 1,819.18% |
Adlai Nortye Ltd American Depositary Shares (ANL) | 821.43% |
Climb Bio (CLYM) | 563.29% |
MMTEC (MTC) | 480.65% |
Q32 Bio (QTTB) | 471.92% |
Forte Biosciences (FBRX) | 435.4% |
Talkspace (TALK) | 429.09% |
Anterix (ATEX) | 372.16% |
agilon health (AGL) | 313.6% |
Entravision Communications (EVC) | 306.82% |
RF Acquisition Corp II Ordinary Shares (RFAI) | 301.96% |
Damora Therapeutics (DMRA) | 291.39% |
Alto Ingredients (ALTO) | 288.24% |
BUUU Group Limited Class A Ordinary Share (BUUU) | 286.38% |
Immix Biopharma (IMMX) | 275.13% |
Shattuck Labs (STTK) | 265.1% |
Century Therapeutics (IPSC) | 258.27% |
Prelude Therapeutics (PRLD) | 256.69% |
Alpha Tau Medical (DRTS) | 244.15% |
Nuvectis Pharma (NVCT) | 235.75% |
Eton Pharmaceuticals (ETON) | 231.91% |
First Tracks Biotherapeutics (TRAX) | 231.54% |
Roma Green Finance Limited Ordinary Shares (ROMA) | 226.84% |
Small-cap stocks are treated as having a market cap between $300M and $2B.