Aclarion (ACON) had the lowest return in Q1 2025 by a US stock, returning -99.2%.

ASSET	QUARTER	% RETURN
Aclarion (ACON)	Q1 2025	-99.18%
Sharps Technology (STSS)	Q1 2025	-98.55%
AEON Biopharma (AEON)	Q1 2025	-98.47%
GlucoTrack (GCTK)	Q1 2025	-97.75%
AGM Group Holdings Inc Class A (AGMH)	Q1 2025	-96.83%
American Rebel (AREB)	Q1 2025	-96.81%
Digital Ally (DGLY)	Q1 2025	-96.49%
Cyngn (CYN)	Q1 2025	-96.46%
Chanson International Holding Class A Ordinary Shares (CHSN)	Q1 2025	-95.48%
Meiwu Technology (WNW)	Q1 2025	-95.46%
Aspire BioPharma (ASBP)	Q1 2025	-94.89%
Bon Natural Life (BON)	Q1 2025	-94.78%
AtlasClear (ATCH)	Q1 2025	-93.68%
Fitell Corporation Ordinary Shares (FTEL)	Q1 2025	-93.46%
Springview Holdings Ltd Class A Ordinary Shares (SPHL)	Q1 2025	-92.43%
NewGenIvf Group Limited Class A Ordinary Shares (NIVF)	Q1 2025	-92.2%
Vyome (HIND)	Q1 2025	-91.96%
TNL Mediagene Ordinary Shares (TNMG)	Q1 2025	-91.35%
Nvni Group Limited Ordinary Shares (NVNI)	Q1 2025	-91.27%
Cloudastructure, Inc Class A Common Stock (CSAI)	Q1 2025	-91.12%
Aditxt (ADTX)	Q1 2025	-90.89%
SMX (Security Matters) Public Limited Company Class A Ordinary Shares (SMX)	Q1 2025	-90.53%
Hyperion DeFi (HYPD)	Q1 2025	-90.38%
XTI Aerospace (XTIA)	Q1 2025	-90.09%
Pliant Therapeutics (PLRX)	Q1 2025	-89.84%