Regencell Bioscience (RGC) has had the highest return this year by a US stock, returning 17,639.5%.

ASSET	YEAR	% RETURN
Regencell Bioscience (RGC)	2025	17,639.52%
Kindly (NAKAW)	2025	6,443.75%
DeFi Development (DFDV)	2025	3,587.03%
HCM II Acquisition (HONDW)	2025	1,968.97%
SRM Entertainment, Inc Common Stock (SRM)	2025	1,411.7%
TMC the metals company Inc Warrants (TMCWW)	2025	1,296.23%
Kindly MD, Inc Common Stock (KDLY)	2025	1,214.52%
Kindly (NAKA)	2025	1,214.52%
K Wave Media (KWMWW)	2025	1,205.83%
M3-Brigade Acquisition V Corp Warrant (MBAVW)	2025	1,157.86%
Diginex Limited Ordinary Shares (DGNX)	2025	893.66%
Asset Entities Inc Class B Common Stock (ASST)	2025	892%
Circle Internet (CRCL)	2025	749.84%
Columbus Circle Capital Corp I Warrant (CCCMW)	2025	693.33%
Oncology Institute (TOI)	2025	648.37%
Oncology Institute (TOIIW)	2025	644.05%
mF International Limited Ordinary Shares (MFI)	2025	630.43%
Protagenic Therapeutics (PTIXW)	2025	627.69%
Dave Inc Warrants (DAVEW)	2025	543.41%
Del Taco Restaurants (TACOW)	2025	529.23%
Webull Corporation Warrants (BULLW)	2025	528.93%
Quantum BioPharma (QNTM)	2025	505.53%
GSR III Acquisition Corp Right (GSRTR)	2025	503.77%
Global Interactive Technologies (GITS)	2025	493.36%
ThredUp (TDUP)	2025	483.33%