Cosmos Health (COSM) had the best day in December 2022 by a US stock on December 16, 2022, returning 497.7%.

ASSET	DATE	% RETURN
Cosmos Health (COSM)	12/16/2022	497.66%
Pharvaris (PHVS)	12/8/2022	173.51%
Exodus Movement (EXOD)	12/12/2022	162.28%
NLS Pharmaceutics (NLSPW)	12/30/2022	141.67%
Healthcare Triangle (HCTI)	12/12/2022	108.24%
Kala Pharmaceuticals (KALA)	12/28/2022	99.36%
GameSquare (GAME)	12/12/2022	94.85%
Moolec Science SA Ordinary Shares (MLEC)	12/27/2022	90.95%
ETHZilla (ETHZ)	12/30/2022	87.29%
Ridgetech (RDGT)	12/12/2022	77.75%
Palisade Bio (PALI)	12/29/2022	75.96%
E-Home Household Service (EJH)	12/22/2022	75.32%
SoundHound AI (SOUN)	12/30/2022	75.25%
Summit Therapeutics (SMMT)	12/6/2022	75%
Soleno Therapeutics (SLNO)	12/19/2022	66.67%
Transcode Therapeutics (RNAZ)	12/7/2022	65.01%
Gorilla Technology (GRRR)	12/21/2022	63.35%
Vivakor (VIVK)	12/1/2022	61.96%
Shuttle Pharmaceuticals (SHPH)	12/2/2022	61.74%
Edible Garden (EDBL)	12/12/2022	60.07%
China SXT Pharmaceuticals (SXTC)	12/12/2022	59.17%
Rent the Runway (RENT)	12/8/2022	55.92%
Caravelle International (HTCO)	12/6/2022	55.87%
Rekor Systems (REKR)	12/21/2022	55.43%
Entero Therapeutics (ENTO)	12/29/2022	54.9%