Hirequest (HQI) had the highest return between 2001 and 2003 by a US stock, returning 5,793,250%.

ASSET	YEARS	% RETURN
Hirequest (HQI)	2001-2003	5,793,250%
Houston American Energy (HUSA)	2001-2003	182,369.65%
ImmunoPrecise Antibodies (HYFT)	2001-2003	122,042.86%
Interlink Electronics (LINK)	2001-2003	46,817.29%
DeFi Technologies (DEFT)	2001-2003	32,900%
MEDIFAST (MED)	2001-2003	9,931.58%
Americas Silver (USAS)	2001-2003	8,347.37%
China Yuchai International (CYD)	2001-2003	4,371.92%
Ziff Davis (ZD)	2001-2003	4,306.81%
Encore Capital (ECPG)	2001-2003	4,214.29%
TherapeuticsMD (TXMD)	2001-2003	3,650%
Xcel Brands (XELB)	2001-2003	3,400%
USANA Health Sciences (USNA)	2001-2003	3,397.94%
Odyssey Marine Exploration (OMEX)	2001-2003	3,233.33%
PetMed Express (PETS)	2001-2003	2,780.19%
Tractor Supply (TSCO)	2001-2003	1,734.98%
Sleep Number (SNBR)	2001-2003	1,622.51%
Stratasys (SSYS)	2001-2003	1,513%
Hecla Mining (HL)	2001-2003	1,373.85%
Sohu (SOHU)	2001-2003	1,238.61%
John B Sanfilippo & Son (JBSS)	2001-2003	1,196.23%
Anika Therapeutics (ANIK)	2001-2003	1,146.64%
Companhia Siderurgica Nacional ADR (SID)	2001-2003	1,133.98%
Live Ventures (LIVE)	2001-2003	1,095.84%
ProPhase Labs (PRPH)	2001-2003	1,094.54%