Insmed (INSM) had the highest return on March 27, 2014 by a large-cap US stock, returning 8.5%.

ASSET	DATE	% RETURN
Insmed (INSM)	3/27/2014	8.53%
Cytokinetics (CYTK)	3/27/2014	8.07%
AXIA Energia (AXIA)	3/27/2014	6.49%
Petroleo Brasileiro Petrobras SA ADR (PBR)	3/27/2014	4.45%
Banco Bradesco S/A ADR (BBDO)	3/27/2014	4.43%
Diamondback Energy (FANG)	3/27/2014	4.34%
Neurocrine Biosciences (NBIX)	3/27/2014	3.63%
Ecopetrol SA ADR (EC)	3/27/2014	3.51%
Leonardo DRS, Inc Common Stock (DRS)	3/27/2014	3.38%
Companhia de Saneamento Basico do Estado de Sao Paulo SABESP ADR (SBS)	3/27/2014	3.35%
Alcoa (AA)	3/27/2014	3.28%
ServiceNow (NOW)	3/27/2014	3.16%
Rambus (RMBS)	3/27/2014	3.09%
Element Solutions (ESI)	3/27/2014	3.03%
Clean Harbors (CLH)	3/27/2014	3.01%
Banco Bradesco SA ADR (BBD)	3/27/2014	2.97%
Sociedad Quimica y Minera de Chile SA ADR B (SQM)	3/27/2014	2.95%
Telefonica Brasil SA ADR (VIV)	3/27/2014	2.85%
Ubiquiti Networks (UI)	3/27/2014	2.84%
Lattice Semiconductor (LSCC)	3/27/2014	2.83%
Applied Opt (AAOI)	3/27/2014	2.72%
Hecla Mining (HL)	3/27/2014	2.62%
Aramark (ARMK)	3/27/2014	2.55%
Five Below (FIVE)	3/27/2014	2.54%
Illumina (ILMN)	3/27/2014	2.49%

Large-cap stocks are treated as having a market cap of $10B+.