Azitra (AZTR) had the highest return between 2021 and 2023 by a US stock, returning 492,757.1%.

ASSET	YEARS	% RETURN
Azitra (AZTR)	2021-2023	492,757.14%
BioNexus Gene Lab Corp Common stock (BGLC)	2021-2023	230,334.78%
Alpha Metallurgical Resources (AMR)	2021-2023	3,045.55%
JIN MEDICAL INTERNATIONAL LTD Ordinary Shares (ZJYL)	2021-2023	3,000.63%
Applied Digital (APLD)	2021-2023	2,895.56%
Atlas Lithium Corporation Common Stock (ATLX)	2021-2023	2,879.05%
Destination XL (DXLG)	2021-2023	1,579.39%
Weatherford International (WFRD)	2021-2023	1,548.33%
RCM Technologies (RCMT)	2021-2023	1,330.54%
Hudson Technologies (HDSN)	2021-2023	1,172.64%
Sigma Lithium Resources (SGML)	2021-2023	1,161.2%
Cresud SACIF y A Warrant (CRESW)	2021-2023	1,060.2%
Vista Oil Gas ADR (VIST)	2021-2023	1,039.38%
Indivior PLC Ordinary Shares (INDV)	2021-2023	1,022.79%
Aehr Test Systems (AEHR)	2021-2023	961.2%
Obsidian Energy (OBE)	2021-2023	911.94%
Peabody Energy (BTU)	2021-2023	898.47%
Permian Resources (PR)	2021-2023	840.72%
Kolibri Global Energy Inc Common stock (KGEI)	2021-2023	837.5%
Super Micro Computer (SMCI)	2021-2023	793.9%
Natural Resource Partners (NRP)	2021-2023	747.88%
Empire Petroleum (EP)	2021-2023	732.6%
Tidewater (TDW)	2021-2023	720.36%
Ramaco Resources (METC)	2021-2023	704.7%
Dillards (DDS)	2021-2023	633.1%