Vertex Pharmaceuticals (VRTX) had its best year since July 24, 1991 in 2000, returning 302.8%.

ASSET	YEAR	% RETURN
Vertex Pharmaceuticals (VRTX)	1991	63.89%
Vertex Pharmaceuticals (VRTX)	1992	-32.76%
Vertex Pharmaceuticals (VRTX)	1993	80.49%
Vertex Pharmaceuticals (VRTX)	1994	-17.81%
Vertex Pharmaceuticals (VRTX)	1995	76.67%
Vertex Pharmaceuticals (VRTX)	1996	57.84%
Vertex Pharmaceuticals (VRTX)	1997	-12.58%
Vertex Pharmaceuticals (VRTX)	1998	-8.81%
Vertex Pharmaceuticals (VRTX)	1999	17.15%
Vertex Pharmaceuticals (VRTX)	2000	302.82%
Vertex Pharmaceuticals (VRTX)	2001	-65.37%
Vertex Pharmaceuticals (VRTX)	2002	-36.24%
Vertex Pharmaceuticals (VRTX)	2003	-35.43%
Vertex Pharmaceuticals (VRTX)	2004	2.13%
Vertex Pharmaceuticals (VRTX)	2005	158.6%
Vertex Pharmaceuticals (VRTX)	2006	34.22%
Vertex Pharmaceuticals (VRTX)	2007	-38.51%
Vertex Pharmaceuticals (VRTX)	2008	30.67%
Vertex Pharmaceuticals (VRTX)	2009	41.54%
Vertex Pharmaceuticals (VRTX)	2010	-18.25%
Vertex Pharmaceuticals (VRTX)	2011	-5.65%
Vertex Pharmaceuticals (VRTX)	2012	23.89%
Vertex Pharmaceuticals (VRTX)	2013	73.31%
Vertex Pharmaceuticals (VRTX)	2014	60.39%
Vertex Pharmaceuticals (VRTX)	2015	4.88%