Tempus AI, Inc Class A Common Stock (TEM) had the lowest return on September 17, 2024 by a large-cap US stock, returning -11.5%.

ASSET	DATE	% RETURN
Tempus AI, Inc Class A Common Stock (TEM)	9/17/2024	-11.47%
Summit Therapeutics (SMMT)	9/17/2024	-7.81%
Ast Spacemobile (ASTS)	9/17/2024	-7.8%
MicroStrategy (MSTR)	9/17/2024	-5.13%
Accenture (ACN)	9/17/2024	-5.09%
Tenet Healthcare (THC)	9/17/2024	-4.49%
Immunitybio (IBRX)	9/17/2024	-4.05%
Snap (SNAP)	9/17/2024	-3.88%
Rocket Lab USA (RKLB)	9/17/2024	-3.76%
Aurora Innovation (AUR)	9/17/2024	-3.45%
CoStar (CSGP)	9/17/2024	-3.32%
argenx NV ADR (ARGX)	9/17/2024	-3.13%
Repligen (RGEN)	9/17/2024	-3.1%
Super Micro Computer (SMCI)	9/17/2024	-2.96%
Thomson Reuters Corporation Common Shares (TRI)	9/17/2024	-2.93%
Monolithic Power Systems (MPWR)	9/17/2024	-2.9%
Encompass Health (EHC)	9/17/2024	-2.88%
Rivian Automotive (RIVN)	9/17/2024	-2.81%
Edwards Lifesciences (EW)	9/17/2024	-2.72%
CoreSite Realty (COR)	9/17/2024	-2.69%
Palo Alto Networks (PANW)	9/17/2024	-2.67%
Jones Lang LaSalle (JLL)	9/17/2024	-2.64%
Atlassian (TEAM)	9/17/2024	-2.54%
Arm Holdings plc American Depositary Shares (ARM)	9/17/2024	-2.54%
Elanco Animal Health (ELAN)	9/17/2024	-2.52%

Large-cap stocks are treated as having a market cap of $10B+.