Fubotv (FUBO) had the lowest return between 2009 and 2018 by a US stock with a market cap of $300M+, returning -100%.

ASSET	YEARS	% RETURN
Fubotv (FUBO)	2009-2018	-100%
Gevo (GEVO)	2009-2018	-100%
Riot Blockchain (RIOT)	2009-2018	-99.89%
Oruka Therapeutics (ORKA)	2009-2018	-99.88%
Centrus Energy (LEU)	2009-2018	-99.86%
Red Cat (RCAT)	2009-2018	-99.86%
Altimmune (ALT)	2009-2018	-99.75%
Mercurity Fintech Holding Inc ADR (MFH)	2009-2018	-99.37%
Ocugen (OCGN)	2009-2018	-99.22%
Capricor Therapeutics (CAPR)	2009-2018	-99.04%
Platinum Group Metals (PLG)	2009-2018	-99.02%
Quantum Computing (QUBT)	2009-2018	-98.93%
FuelCell Energy (FCEL)	2009-2018	-98.82%
Civitas Resources (CIVI)	2009-2018	-98.8%
Blue Ridge Bankshares (BRBS)	2009-2018	-98.7%
Babcock & Wilcox Enterprises (BW)	2009-2018	-98.23%
Tidewater (TDW)	2009-2018	-98.18%
Comstock Resources (CRK)	2009-2018	-98%
Viridian Therapeutics (VRDN)	2009-2018	-97.82%
Celldex Therapeutics (CLDX)	2009-2018	-97.53%
Lightbridge (LTBR)	2009-2018	-97.48%
Stereotaxis (STXS)	2009-2018	-97.44%
Talos Energy (TALO)	2009-2018	-97.38%
InnovAge (INNV)	2009-2018	-97.31%
Euroseas (ESEA)	2009-2018	-97.28%