Plumas Bancorp (PLBC) had the lowest return between 2000 and 2009 by a US stock, returning -100%.

ASSET	YEARS	% RETURN
Plumas Bancorp (PLBC)	2000-2009	-100%
Nocera (NCRA)	2000-2009	-100%
Orange County Bancorp (OBT)	2000-2009	-100%
Zynex (ZYXI)	2000-2009	-100%
America Movil SAB de CV ADR (AMX)	2000-2009	-100%
Fortis (FTS)	2000-2009	-100%
Molson Coors Beverage (TAP.A)	2000-2009	-100%
Stantec (STN)	2000-2009	-99.98%
Precision Optics Corporation, Inc Common stock (POCI)	2000-2009	-99.96%
Neonode (NEON)	2000-2009	-99.95%
Natural Health Trend (NHTC)	2000-2009	-99.92%
Red Cat (RCAT)	2000-2009	-99.92%
SWK (SWKH)	2000-2009	-99.92%
Travere Therapeutics (TVTX)	2000-2009	-99.85%
Netcapital (NCPL)	2000-2009	-99.83%
Coda Octopus (CODA)	2000-2009	-99.81%
Gilat Satellite Networks (GILT)	2000-2009	-99.81%
Heritage Global (HGBL)	2000-2009	-99.74%
Usio (USIO)	2000-2009	-99.74%
eGain (EGAN)	2000-2009	-99.73%
Silvercorp Metals (SVM)	2000-2009	-99.57%
Marker Therapeutics (MRKR)	2000-2009	-99.57%
Ammo (POWW)	2000-2009	-99.35%
Armata Pharmaceuticals (ARMP)	2000-2009	-99.31%
Cantaloupe (CTLP)	2000-2009	-99.27%