Yoshitsu Co Ltd ADR (TKLF) had the lowest return in Q1 2022 by a US stock, returning -94.8%.

ASSET	QUARTER	% RETURN
Yoshitsu Co Ltd ADR (TKLF)	Q1 2022	-94.83%
Kodiak Sciences (KOD)	Q1 2022	-90.98%
Tantech (TANH)	Q1 2022	-89.65%
Jowell Global (JWEL)	Q1 2022	-89.24%
ProQR Therapeutics (PRQR)	Q1 2022	-88.74%
Revelation Biosciences (REVB)	Q1 2022	-88.69%
TDH (PETZ)	Q1 2022	-88.43%
Mega Matrix (MPU)	Q1 2022	-83.4%
Jasper Therapeutics (JSPRW)	Q1 2022	-82.06%
Aligos Therapeutics (ALGS)	Q1 2022	-81.98%
Sunshine Biopharma (SBFM)	Q1 2022	-79.2%
Dingdong (Cayman) Limited ADR (DDL)	Q1 2022	-78.43%
Revelation Biosciences (REVBW)	Q1 2022	-78.05%
MEI Pharma, Inc Common Stock (LITS)	Q1 2022	-77.78%
MEI Pharma (MEIP)	Q1 2022	-77.69%
Surrozen Inc Warrant (SRZNW)	Q1 2022	-77.68%
Annexon (ANNX)	Q1 2022	-76.38%
Ensysce Biosciences (ENSC)	Q1 2022	-75.8%
Bioatla (BCAB)	Q1 2022	-75.6%
Catheter Precision (VTAK)	Q1 2022	-74.68%
Cerberus Cyber Sentinel (CISO)	Q1 2022	-74.67%
Vivakor (VIVK)	Q1 2022	-74.6%
Amber International (AMBR)	Q1 2022	-74.4%
Akanda (AKAN)	Q1 2022	-73.53%
Ucloudlink (UCL)	Q1 2022	-73.29%