Allarity Therapeutics (ALLR) had the lowest return in 2023 by a US stock in the Nasdaq Composite (IXIC), returning -99.9%.

ASSET	YEAR	% RETURN
Allarity Therapeutics (ALLR)	2023	-99.86%
Ascent Solar Technologies, Inc Common Stock (ASTI)	2023	-99.73%
SMX (Security Matters) Public Limited Company Class A Ordinary Shares (SMX)	2023	-99.69%
Falcon's Beyond Global, Inc Class A Common Stock (FBYD)	2023	-99.57%
Avalo Therapeutics (AVTX)	2023	-99.25%
AgriFORCE Growing Systems (AGRI)	2023	-99.16%
Biodexa Pharmaceticals (BDRX)	2023	-99.15%
Faraday Future Intelligent Electric (FFIE)	2023	-99.06%
Transcode Therapeutics (RNAZ)	2023	-98.74%
22nd Century (XXII)	2023	-98.64%
ZyVersa Therapeutics (ZVSA)	2023	-98.48%
Volcon (VLCN)	2023	-98.11%
Hub Cyber Security Ltd Ordinary Shares (HUBC)	2023	-98.07%
Infobird (IFBD)	2023	-97.82%
U Power Limited Ordinary Shares (UCAR)	2023	-97.73%
Jaguar Animal Health (JAGX)	2023	-97.69%
ReShape Lifesciences (RSLS)	2023	-97.41%
Tivic Health Systems (TIVC)	2023	-97.31%
C3is (CISS)	2023	-97.06%
Clearmind Medicine Inc Common Shares (CMND)	2023	-97.04%
Cenntro Electric (CENN)	2023	-96.73%
SenesTech (SNES)	2023	-96.56%
SINTX Technologies (SINT)	2023	-96.04%
Lion (LGHL)	2023	-95.97%
Cerberus Cyber Sentinel (CISO)	2023	-95.92%