QXO (QXO) had the highest return between 2011 and 2012 by a large-cap US stock, returning 4,032,075%.

ASSET	YEARS	% RETURN
QXO (QXO)	2011-2012	4,032,075%
Expedia (EXPE)	2011-2012	512.32%
Regeneron Pharmaceuticals (REGN)	2011-2012	423.31%
Cheniere Energy (LNG)	2011-2012	234.16%
Domino's Pizza Inc Common Stock (DPZ)	2011-2012	192.28%
Ulta Beauty (ULTA)	2011-2012	191.12%
Generac (GNRC)	2011-2012	179.73%
Builders FirstSource (BLDR)	2011-2012	179%
Jazz Pharmaceuticals (JAZZ)	2011-2012	167.86%
Contura Energy (CTRA)	2011-2012	161.16%
HF Sinclair (DINO)	2011-2012	158.24%
PulteGroup (PHM)	2011-2012	138.32%
Dillard's (DDS)	2011-2012	132.46%
Tyler Technologies (TYL)	2011-2012	131.33%
Lululemon Athletica (LULU)	2011-2012	119.71%
Visa Inc Class A (V)	2011-2012	118.73%
Seagate Technology (STX)	2011-2012	118.29%
Mastercard (MA)	2011-2012	117.96%
Grupo Aeroportuario del Sureste SAB de CV ADR (ASR)	2011-2012	117.45%
Biogen (BIIB)	2011-2012	116.27%
LyondellBasell Industries (LYB)	2011-2012	112.44%
Targa Resources (TRGP)	2011-2012	108.66%
Lennar (LEN)	2011-2012	107.74%
Transdigm (TDG)	2011-2012	106.16%
Monster Beverage (MNST)	2011-2012	100.72%

Large-cap stocks are treated as having a market cap of $10B+.