QXO (QXO) had the highest return between 2010 and 2014 by a US stock with a market cap of $1B+, returning 7,392,225%.

ASSET	YEARS	% RETURN
QXO (QXO)	2010-2014	7,392,225%
Inventrust Properties (IVT)	2010-2014	1,067,615%
Ferguson (FERG)	2010-2014	492,162.92%
Sandstorm Gold Ltd N (SAND)	2010-2014	363,244.44%
Vipshop (VIPS)	2010-2014	3,156.64%
Cheniere Energy (LNG)	2010-2014	2,716%
Par Pacific (PARR)	2010-2014	2,608.33%
ACADIA Pharmaceuticals (ACAD)	2010-2014	2,305.3%
Jazz Pharmaceuticals (JAZZ)	2010-2014	1,931.39%
Patrick Industries (PATK)	2010-2014	1,687.88%
Regeneron Pharmaceuticals (REGN)	2010-2014	1,592.45%
Acadia Healthcare (ACHC)	2010-2014	1,266.29%
Travere Therapeutics (TVTX)	2010-2014	1,260%
Aris Mining (ARMN)	2010-2014	1,240.65%
Astronics (ATRO)	2010-2014	1,237.06%
Nexstar Broadcasting (NXST)	2010-2014	1,220.98%
Pacira BioSciences (PCRX)	2010-2014	1,166.57%
Domino's Pizza Inc Common Stock (DPZ)	2010-2014	1,124.21%
Tesla (TSLA)	2010-2014	1,070.55%
Lithia Motors (LAD)	2010-2014	1,014.68%
American Airlines (AAL)	2010-2014	1,013.65%
Bausch Health Companies (BHC)	2010-2014	979.14%
Virtus Investment Partners (VRTS)	2010-2014	959.12%
United Rentals (URI)	2010-2014	928.33%
Under Armour Inc A (UAA)	2010-2014	888.71%