Applied Digital (APLD) had the highest return between 2021 and 2023 by a US stock with a market cap of $5B+, returning 17,873.3%.

ASSET	YEARS	% RETURN
Applied Digital (APLD)	2021-2023	17,873.33%
Permian Resources (PR)	2021-2023	840.69%
Super Micro Computer (SMCI)	2021-2023	793.9%
Dillard's (DDS)	2021-2023	633.1%
Chord Energy (CHRD)	2021-2023	545.53%
QXO (QXO)	2021-2023	539.53%
Globalstar, Inc Common Stock (GSAT)	2021-2023	487.88%
ELF Beauty (ELF)	2021-2023	470.29%
Avis Budget (CAR)	2021-2023	394.75%
Symbotic (SYM)	2021-2023	394.03%
Modine Manufacturing (MOD)	2021-2023	373.06%
Matador Resources (MTDR)	2021-2023	371.47%
Sterling Construction (STRL)	2021-2023	370.72%
Antero Resources (AR)	2021-2023	307.18%
Nuvalent (NUVL)	2021-2023	306.57%
Builders FirstSource (BLDR)	2021-2023	304.7%
Cytokinetics (CYTK)	2021-2023	301.59%
Comfort Systems USA (FIX)	2021-2023	296.47%
Rambus (RMBS)	2021-2023	289.11%
Marathon Petroleum (MPC)	2021-2023	288.51%
Coca-Cola Consolidated (COKE)	2021-2023	287.43%
NVIDIA (NVDA)	2021-2023	278.76%
Frontline (FRO)	2021-2023	271.83%
GameStop (GME)	2021-2023	269.05%
Diamondback Energy (FANG)	2021-2023	263.93%